BACKGROUND: Acinetobacter baumannii has evolved from an opportunistic pathogen into a common and persistent nosocomial bacterium capable of causing severe infections during endemic and epidemic periods. METHODS: The study period extended from January 1999 to December 2011 and involved patients hospitalized at the Hospital Civil de Guadalajara, Fray Antonio Alcalde, Jalisco, Mexico. From each patient, a single isolate was obtained, and a total of 3,680 unique isolates were collected. Susceptibility tests were performed according to the guidelines of the Clinical and Laboratory Standards Institute. RESULTS: A. baumannii has disseminated throughout the Hospital Civil de Guadalajara, Fray Antonio Alcalde, since 1999. A. baumannii isolates obtained from patients treated in the adult intensive care unit represent the majority of the isolates that have been collected. In addition, A. baumannii was isolated from the adult neurosurgical ward and the adult internal medicine ward, and these isolates were frequently obtained from secretions. A persistent decrease in the susceptibility of A. baumannii isolates to meropenem (92% in 1999 to 12% in 2011), imipenem and amikacin has been observed. CONCLUSIONS: A. baumannii became an endemic nosocomial pathogen during the study period at the Hospital Civil de Guadalajara, Fray Antonio Alcalde, and has exhibited a persistent decrease in susceptibility to all categories of antimicrobial agents over the past 13 years.
BACKGROUND:Acinetobacter baumannii has evolved from an opportunistic pathogen into a common and persistent nosocomial bacterium capable of causing severe infections during endemic and epidemic periods. METHODS: The study period extended from January 1999 to December 2011 and involved patients hospitalized at the Hospital Civil de Guadalajara, Fray Antonio Alcalde, Jalisco, Mexico. From each patient, a single isolate was obtained, and a total of 3,680 unique isolates were collected. Susceptibility tests were performed according to the guidelines of the Clinical and Laboratory Standards Institute. RESULTS:A. baumannii has disseminated throughout the Hospital Civil de Guadalajara, Fray Antonio Alcalde, since 1999. A. baumannii isolates obtained from patients treated in the adult intensive care unit represent the majority of the isolates that have been collected. In addition, A. baumannii was isolated from the adult neurosurgical ward and the adult internal medicine ward, and these isolates were frequently obtained from secretions. A persistent decrease in the susceptibility of A. baumannii isolates to meropenem (92% in 1999 to 12% in 2011), imipenem and amikacin has been observed. CONCLUSIONS:A. baumannii became an endemic nosocomial pathogen during the study period at the Hospital Civil de Guadalajara, Fray Antonio Alcalde, and has exhibited a persistent decrease in susceptibility to all categories of antimicrobial agents over the past 13 years.
Authors: Roberto Rosales-Reyes; Catalina Gayosso-Vázquez; José Luis Fernández-Vázquez; Ma Dolores Jarillo-Quijada; César Rivera-Benítez; José Ignacio Santos-Preciado; María Dolores Alcántar-Curiel Journal: PLoS One Date: 2017-08-10 Impact factor: 3.240
Authors: Elvira Garza-González; Rayo Morfín-Otero; Soraya Mendoza-Olazarán; Paola Bocanegra-Ibarias; Samantha Flores-Treviño; Eduardo Rodríguez-Noriega; Alfredo Ponce-de-León; Domingo Sanchez-Francia; Rafael Franco-Cendejas; Sara Arroyo-Escalante; Consuelo Velázquez-Acosta; Fabián Rojas-Larios; Luis J Quintanilla; Joyarit Y Maldonado-Anicacio; Rafael Martínez-Miranda; Heidy L Ostos-Cantú; Abraham Gomez-Choel; Juan L Jaime-Sanchez; Laura K Avilés-Benítez; José M Feliciano-Guzmán; Cynthia D Peña-López; Carlos A Couoh-May; Aaron Molina-Jaimes; Elda G Vázquez-Narvaez; Joaquín Rincón-Zuno; Raúl Rivera-Garay; Aurelio Galindo-Espinoza; Andrés Martínez-Ramirez; Javier P Mora; Reyna E Corte-Rojas; Ismelda López-Ovilla; Víctor A Monroy-Colin; Juan M Barajas-Magallón; Cecilia T Morales-De-la-Peña; Efrén Aguirre-Burciaga; Mabel Coronado-Ramírez; Alina A Rosales-García; María-de-J Ayala-Tarín; Silvia Sida-Rodríguez; Bertha A Pérez-Vega; América Navarro-Rodríguez; Gloria E Juárez-Velázquez; Carlos Miguel Cetina-Umaña; Juan P Mena-Ramírez; Jorge Canizales-Oviedo; Martha Irene Moreno-Méndez; Daniel Romero-Romero; Alejandra Arévalo-Mejía; Dulce Isabel Cobos-Canul; Gilberto Aguilar-Orozco; Jesús Silva-Sánchez; Adrián Camacho-Ortiz Journal: PLoS One Date: 2019-03-26 Impact factor: 3.240
Authors: María Dolores Alcántar-Curiel; Roberto Rosales-Reyes; Ma Dolores Jarillo-Quijada; Catalina Gayosso-Vázquez; José Luis Fernández-Vázquez; José Eduardo Toledano-Tableros; Silvia Giono-Cerezo; Paola Garza-Villafuerte; Arath López-Huerta; Daniela Vences-Vences; Rayo Morfín-Otero; Eduardo Rodríguez-Noriega; María Del Rocío López-Álvarez; María Del Carmen Espinosa-Sotero; José Ignacio Santos-Preciado Journal: Front Microbiol Date: 2019-09-20 Impact factor: 5.640
Authors: Lucía Graña-Miraglia; Luis F Lozano; Consuelo Velázquez; Patricia Volkow-Fernández; Ángeles Pérez-Oseguera; Miguel A Cevallos; Santiago Castillo-Ramírez Journal: Front Microbiol Date: 2017-09-20 Impact factor: 5.640
Authors: María Dolores Alcántar-Curiel; Carmen Alejandra Ledezma-Escalante; Ma Dolores Jarillo-Quijada; Catalina Gayosso-Vázquez; Rayo Morfín-Otero; Eduardo Rodríguez-Noriega; María Lilia Cedillo-Ramírez; José Ignacio Santos-Preciado; Jorge A Girón Journal: Biomed Res Int Date: 2018-09-23 Impact factor: 3.411