Literature DB >> 23838503

Delayed diagnosis of oral squamous cell carcinoma following dental treatment.

T Singh1, M Schenberg.   

Abstract

INTRODUCTION: Oral squamous cell carcinoma (SCC) can present with a wide range of clinical appearances. Consequently, an oral SCC, particularly in its early stage, may not be considered suspicious by a clinician, thereby delaying diagnosis. Delayed diagnosis of an oral SCC could result in more advanced disease at the time of treatment, leading to more extensive and costly treatment, greater morbidity and poorer survival. The aim of this study was to identify cases of oral SCC treated at Southern Heath (Melbourne, Australia) with a history of prediagnosis dental treatment, and to determine the delay between dental treatment and appropriate surgical assessment of the oral SCC.
METHODS: Patients were identified from the head and neck tumour database at Southern Health who met the inclusion criteria and relevant data were recorded.
RESULTS: Twelve patients met the inclusion criteria and 83% of cases involved the mandible. Dental extraction was the most common prediagnosis treatment performed (75%). The average delay from dental treatment to surgical assessment was just over eight weeks and all patients were found to have stage IV disease. Most patients had received extensive surgical resections (83%), neck dissections (75%) and adjunctive therapy (83%).
CONCLUSIONS: Oral SCC can sometimes be difficult to diagnose, which can result in more extensive treatment and greater morbidity. Health professionals and patients need to be aware that non-healing oral lesions, even after dental treatment such as a dental extraction, need to be considered as suspicious and an appropriate surgical referral should be made.

Entities:  

Mesh:

Year:  2013        PMID: 23838503      PMCID: PMC4165143          DOI: 10.1308/003588413X13629960045599

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  10 in total

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10.  Referral patterns of patients with oral squamous cell carcinoma, Australia.

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  10 in total
  3 in total

1.  A novel long non-coding RNA, AC012456.4, as a valuable and independent prognostic biomarker of survival in oral squamous cell carcinoma.

Authors:  Xuegang Hu; Zailing Qiu; Jianchai Zeng; Tingting Xiao; Zhihong Ke; Hongbing Lyu
Journal:  PeerJ       Date:  2018-08-13       Impact factor: 2.984

2.  Delayed diagnosis in the maxillofacial region: Two case reports.

Authors:  Ebtihal H Zain-Alabdeen; Raed I Al-Sadhan; Faisal S AlSuhaim; Khalid M AlMutairi
Journal:  J Taibah Univ Med Sci       Date:  2017-05-27

3.  LncRNA ELF3-AS1 is involved in the regulation of oral squamous cell carcinoma cell proliferation by reprogramming glucose metabolism.

Authors:  Hongxing Chu; Zhengqiang Li; Zekun Gan; Zinan Yang; Zhenzhen Wu; Mingdeng Rong
Journal:  Onco Targets Ther       Date:  2019-08-22       Impact factor: 4.147

  3 in total

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