Literature DB >> 2383591

The primary structure of the rat insulin-like growth factor II gene region.

K Ikejiri1, T Ueno, T Matsuguchi, K Takahashi, H Endo, M Yamamoto.   

Abstract

Complete nucleotide sequences of the rat insulin-like growth factor II gene region including 5' 18 kilobases (kb) up to the insulin gene, all exonic and intronic, and 3' 6 kb sequences were determined. Among these sequences several repetitive stretches became evident besides integration of type II Alu and identifier sequences. They were: (1) twelve repetitions of about 100 base pair (bp) units; (2) duplication of 60 bp units; (3) triplication of a 24 bp unit; and (4) 41-fold expansion of 12-15 bp units.

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Year:  1990        PMID： 2383591     DOI： 10.1016/0167-4781(90)90110-n

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  5 in total

Review 1.  Transcriptional regulation and biological significance of the insulin like growth factor II gene.

Authors:  W Engström; A Shokrai; K Otte; M Granérus; A Gessbo; P Bierke; A Madej; M Sjölund; A Ward
Journal:  Cell Prolif       Date:  1998 Oct-Dec       Impact factor: 6.831

2.  Identification of a novel transcription unit in the human insulin-like growth factor-II gene.

Authors:  K Ikejiri; T Wasada; K Haruki; N Hizuka; Y Hirata; M Yamamoto
Journal:  Biochem J       Date:  1991-12-01       Impact factor: 3.857

3.  A conserved structural element in horse and mouse IGF2 genes binds a methylation sensitive factor.

Authors:  K Otte; D Choudhury; M Charalambous; W Engström; B Rozell
Journal:  Nucleic Acids Res       Date:  1998-04-01       Impact factor: 16.971

4.  The liver-specific promoter of the human insulin-like growth factor II gene is activated by CCAAT/enhancer binding protein (C/EBP).

Authors:  M A van Dijk; R J Rodenburg; P Holthuizen; J S Sussenbach
Journal:  Nucleic Acids Res       Date:  1992-06-25       Impact factor: 16.971

5.  Insulin-like growth factor-II gene expression in a rat insulin-producing beta-cell line (INS-1) is regulated by glucose.

Authors:  M Asfari; W De; M Nöel; P E Holthuizen; P Czernichow
Journal:  Diabetologia       Date:  1995-08       Impact factor: 10.122
  5 in total

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