Literature DB >> 23835898

Low-toxicity dusts: current exposure guidelines are not sufficiently protective.

John W Cherrie1, Lisa M Brosseau, Alastair Hay, Kenneth Donaldson.   

Abstract

Exposure to low-toxicity dusts, which have previously been viewed as 'nuisance dusts', can cause chronic obstructive pulmonary disease or other nonmalignant respiratory disease. In Britain, the 'de facto' airborne exposure limits for these dusts have remained unchanged for >30 years; currently, they are 10mg m(-3) for inhalable dust and 4mg m(-3) for respirable dust. During this time, exposures in industry have decreased and although in the past, many occupational dust exposures may have exceeded these limits, today this is less likely. However, there is good evidence from epidemiology and toxicology studies that current dust exposures may still present a risk to workers and that for some of those who are affected, there are devastating health consequences. Numerous researchers and others have drawn attention to the necessity to control dust exposures to levels lower than are currently accepted in Britain. It is proposed that until regulators agree on the safe occupational exposure limits for low-toxicity dusts, health and safety professionals should consider 1mg m(-3) of respirable dusts as a more appropriate guideline than the value of 4mg m(-3) currently used in Britain.

Entities:  

Keywords:  COPD; COSHH; OEL; inhalable dust; lung function; respirable dust

Mesh:

Substances:

Year:  2013        PMID: 23835898     DOI: 10.1093/annhyg/met038

Source DB:  PubMed          Journal:  Ann Occup Hyg        ISSN: 0003-4878


  8 in total

Review 1.  Characterizing risk assessments for the development of occupational exposure limits for engineered nanomaterials.

Authors:  P A Schulte; E D Kuempel; N M Drew
Journal:  Regul Toxicol Pharmacol       Date:  2018-03-21       Impact factor: 3.271

2.  Respiratory Health Effects of Exposure to Ambient Particulate Matter and Bioaerosols.

Authors:  Savannah M Mack; Amy K Madl; Kent E Pinkerton
Journal:  Compr Physiol       Date:  2019-12-18       Impact factor: 9.090

3.  Biokinetics of Nanomaterials: the Role of Biopersistence.

Authors:  Peter Laux; Christian Riebeling; Andy M Booth; Joseph D Brain; Josephine Brunner; Cristina Cerrillo; Otto Creutzenberg; Irina Estrela-Lopis; Thomas Gebel; Gunnar Johanson; Harald Jungnickel; Heiko Kock; Jutta Tentschert; Ahmed Tlili; Andreas Schäffer; Adriënne J A M Sips; Robert A Yokel; Andreas Luch
Journal:  NanoImpact       Date:  2017-03-22

4.  Human and animal evidence supports lower occupational exposure limits for poorly-soluble respirable particles: Letter to the Editor re: 'Low-toxicity dusts: Current exposure guidelines are not sufficiently protective' by Cherrie, Brosseau, Hay and Donaldson.

Authors:  Eileen D Kuempel; Michael D Attfield; Leslie T Stayner; Vincent Castranova
Journal:  Ann Occup Hyg       Date:  2014-09-05

5.  Exposure to airborne particles and volatile organic compounds from polyurethane molding, spray painting, lacquering, and gluing in a workshop.

Authors:  Bjarke Mølgaard; Anna-Kaisa Viitanen; Anneli Kangas; Marika Huhtiniemi; Søren Thor Larsen; Esa Vanhala; Tareq Hussein; Brandon E Boor; Kaarle Hämeri; Antti Joonas Koivisto
Journal:  Int J Environ Res Public Health       Date:  2015-04-02       Impact factor: 3.390

6.  Translational toxicology in setting occupational exposure limits for dusts and hazard classification - a critical evaluation of a recent approach to translate dust overload findings from rats to humans.

Authors:  Peter Morfeld; Joachim Bruch; Len Levy; Yufanyi Ngiewih; Ishrat Chaudhuri; Henry J Muranko; Ross Myerson; Robert J McCunney
Journal:  Part Fibre Toxicol       Date:  2015-04-23       Impact factor: 9.400

7.  Occupational Exposures in an Equestrian Centre to Respirable Dust and Respirable Crystalline Silica.

Authors:  Kathleen Bulfin; Hilary Cowie; Karen S Galea; Alison Connolly; Marie Ann Coggins
Journal:  Int J Environ Res Public Health       Date:  2019-09-03       Impact factor: 3.390

Review 8.  McIntyre Powder and its potential contributions to cardiovascular disease risk: A literature review through the McIntyre Powder historical lens.

Authors:  Andrew Zarnke; Christine Oliver; Sandra Dorman
Journal:  Am J Ind Med       Date:  2022-07-21       Impact factor: 3.079

  8 in total

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