Literature DB >> 2383476

Resection guided by antibodies (REGAJ): a diagnostic procedure during second-look operation in ovarian cancer patients.

W Jäger1, H Feistel, E M Paterok, G Ronay, A H Tulusan, F Wolf, N Lang.   

Abstract

A hand-held probe has been used to localise the 131I-labelled antibody OC125 during second-look operation (SLO) in 22 ovarian cancer patients. In six patients microscopic cancer was detected with the procedure and a further six patients with areas of increased radioactivity during SLO developed recurrent disease within 1-4 months. We suggest examining resection guided by antibodies as a possible means of removing antigen-producing cancerous tissues during surgery.

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Year:  1990        PMID： 2383476      PMCID： PMC2149505     

Source DB:  PubMed          Journal:  Br J Cancer Suppl        ISSN： 0306-9443


  8 in total

1.  Serum CA-125 as a guideline for the timing of a second-look operation and second-line treatment in ovarian cancer.

Authors:  W Jäger; R Adam; L Wildt; N Lang
Journal:  Arch Gynecol Obstet       Date:  1988       Impact factor: 2.344

Review 2.  Is routine second-look laparotomy for ovarian cancer justified?

Authors:  E W Sonnendecker
Journal:  Gynecol Oncol       Date:  1988-10       Impact factor: 5.482

3.  The changing role of "second-look" laparotomy in the management of epithelial carcinoma of the ovary.

Authors:  G C Stuart; M Jeffries; J L Stuart; R J Anderson
Journal:  Am J Obstet Gynecol       Date:  1982-03-15       Impact factor: 8.661

4.  Recurrence after negative second-look laparotomy for ovarian cancer: analysis of risk factors.

Authors:  S C Rubin; W J Hoskins; T B Hakes; M Markman; J M Cain; J L Lewis
Journal:  Am J Obstet Gynecol       Date:  1988-11       Impact factor: 8.661

5.  Distribution and pharmacokinetics of radiolabeled monoclonal antibody OC 125 after intravenous and intraperitoneal administration in gynecologic tumors.

Authors:  H J Haisma; K R Moseley; A Battaile; T C Griffiths; R C Knapp
Journal:  Am J Obstet Gynecol       Date:  1988-10       Impact factor: 8.661

6.  Second-look laparotomy in managing epithelial ovarian carcinoma.

Authors:  J Dauplat; J P Ferriere; M Gorbinet; M Legros; P Chollet; B Giraud; R Plagne
Journal:  Cancer       Date:  1986-04-15       Impact factor: 6.860

7.  Tissue distribution of a coelomic-epithelium-related antigen recognized by the monoclonal antibody OC125.

Authors:  S E Kabawat; R C Bast; A K Bhan; W R Welch; R C Knapp; R B Colvin
Journal:  Int J Gynecol Pathol       Date:  1983       Impact factor: 2.762

8.  Immunoscintigraphy of recurrences of gynecologic carcinomas.

Authors:  J F Chatal; P Fumoleau; J C Saccavini; P Thedrez; C Curtet; A Bianco-Arco; A Chetanneau; P Peltier; M Kremer; Y Guillard
Journal:  J Nucl Med       Date:  1987-12       Impact factor: 10.057
  8 in total
  3 in total

1.  Distribution of radiolabelled anti-CA125 monoclonal antibody OC125-F(ab)2-fragment following resection guided by antibodies (REGAJ) in ovarian cancer patients.

Authors:  M M Uttenreuther-Fischer; H Feistel; F Wolf; W Jäger
Journal:  J Clin Lab Anal       Date:  1997       Impact factor: 2.352

Review 2.  A comprehensive overview of radioguided surgery using gamma detection probe technology.

Authors:  Stephen P Povoski; Ryan L Neff; Cathy M Mojzisik; David M O'Malley; George H Hinkle; Nathan C Hall; Douglas A Murrey; Michael V Knopp; Edward W Martin
Journal:  World J Surg Oncol       Date:  2009-01-27       Impact factor: 2.754

3.  Immunoscintigraphic localization of renal tumours in an extracorporeal perfusion model with a monoclonal antibody against gamma-glutamyltransferase.

Authors:  P Fischer; R P Baum; M Tauber; W Boeckmann; S Weier; J E Scherberich
Journal:  Cancer Immunol Immunother       Date:  1992       Impact factor: 6.968
  3 in total

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