| Literature DB >> 23834264 |
Italo A Sanhueza1, Karl J Bonney, Mads C Nielsen, Franziska Schoenebeck.
Abstract
The (trifluoromethyl)stannane reagent, Bu3SnCF3, was found to react under CsF activation with ketones and aldehydes to the corresponding trifluoromethylated stannane ether intermediates at room temperature in high yield. Only a mildly acidic extraction (aqueous NH4Cl) is required to release the corresponding trifluoromethyl alcohol products. The protocol is compatible with acid-sensitive functional groups.Entities:
Mesh：
Substances：
Year: 2013 PMID： 23834264 DOI： 10.1021/jo401099e
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354