Literature DB >> 23833289

Keep PNUTS in your heart.

Francesco S Loffredo1, James R Pancoast, Richard T Lee.   

Abstract

Aging is a major factor in many cardiovascular diseases. The molecular factors that regulate age-related changes in cardiac physiology and contribute to the increased cardiovascular risk in the elderly are not fully understood. A study recently published in Nature suggests a specific role for microRNAs (miRNAs) in regulating cardiac aging and function, challenging the concept that aging is an inevitable process in the heart.

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Year:  2013        PMID： 23833289     DOI： 10.1161/CIRCRESAHA.113.301933

Source DB:  PubMed          Journal:  Circ Res        ISSN： 0009-7330            Impact factor:   17.367


  6 in total

Review 1.  Role of circulating factors in cardiac aging.

Authors:  Antonio Cannatà; Gabriella Marcon; Giovanni Cimmino; Luca Camparini; Giulio Ciucci; Gianfranco Sinagra; Francesco S Loffredo
Journal:  J Thorac Dis       Date:  2017-03       Impact factor: 2.895

Review 2.  Heart failure with preserved ejection fraction: molecular pathways of the aging myocardium.

Authors:  Francesco S Loffredo; Andriana P Nikolova; James R Pancoast; Richard T Lee
Journal:  Circ Res       Date:  2014-06-20       Impact factor: 17.367

3.  Serum Extracellular Vesicles Retard H9C2 Cell Senescence by Suppressing miR-34a Expression.

Authors:  Yang Liu; Zhuyuan Liu; Yuan Xie; Cuimei Zhao; Jiahong Xu
Journal:  J Cardiovasc Transl Res       Date:  2018-11-29       Impact factor: 4.132

Review 4.  Impact of miRNAs on cardiovascular aging.

Authors:  Seahyoung Lee; Eunhyun Choi; Min-Ji Cha; Ae-Jun Park; Cheesoon Yoon; Ki-Chul Hwang
Journal:  J Geriatr Cardiol       Date:  2015-09       Impact factor: 3.327

5.  Silencing of miR-34a attenuates cardiac dysfunction in a setting of moderate, but not severe, hypertrophic cardiomyopathy.

Authors:  Bianca C Bernardo; Xiao-Ming Gao; Yow Keat Tham; Helen Kiriazis; Catherine E Winbanks; Jenny Y Y Ooi; Esther J H Boey; Susanna Obad; Sakari Kauppinen; Paul Gregorevic; Xiao-Jun Du; Ruby C Y Lin; Julie R McMullen
Journal:  PLoS One       Date:  2014-02-27       Impact factor: 3.240

6.  PD-1 inhibitor inducing exosomal miR-34a-5p expression mediates the cross talk between cardiomyocyte and macrophage in immune checkpoint inhibitor-related cardiac dysfunction.

Authors:  Wenzheng Xia; Hanbin Chen; Didi Chen; Congying Xie; Meng Hou; Yijia Ye
Journal:  J Immunother Cancer       Date:  2020-10       Impact factor: 13.751
  6 in total

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