Literature DB >> 23831724

Efficacy of Clostridium botulinum types C and D toxoid vaccination in Danish cows.

Monika Krüger1, Marie Skau, Awad Ali Shehata, Wieland Schrödl.   

Abstract

In the present study the efficacy Botulism vaccine (formalinised aluminum hydroxide gel adsorbed toxoid of Clostridium botulinum types C and D) was evaluated in four Danish dairy cows under field conditions. Other four dairy herds were unvaccinated. Blood serum of all animals was analyzed for specific C. botulinum types A, B, C, D and E antibodies using a developed ELISA. Feces of all animals were analyzed for botulinum neurotoxins (BoNTs) and C. botulinum spores. C. botulinum types C and D antibodies were significantly (p < 0.05) increased in vaccinated animals. Vaccination with botulism vaccine significantly reduced (p < 0.001) BoNTs and C. botulinum spores in cattle feces. Our findings represent that C. botulinum vaccination increases specific blood serum antibodies and reduces free BoNTs and C. botulinum spores in feces.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Botulinum neurotoxins; Botulism; Clostridium botulinum; ELISA; Vaccination

Mesh：

Substances：

Year:  2013        PMID： 23831724     DOI： 10.1016/j.anaerobe.2013.06.011

Source DB:  PubMed          Journal:  Anaerobe        ISSN： 1075-9964            Impact factor:   3.331


  9 in total

1.  Detection of Clostridium botulinum in liquid manure and biogas plant wastes.

Authors:  Jürgen Neuhaus; Wieland Schrödl; Awad A Shehata; Monika Krüger
Journal:  Folia Microbiol (Praha)       Date:  2015-03-10       Impact factor: 2.099

2.  Molecular Evolutionary Constraints that Determine the Avirulence State of Clostridium botulinum C2 Toxin.

Authors:  A Prisilla; R Prathiviraj; P Chellapandi
Journal:  J Mol Evol       Date:  2017-04-05       Impact factor: 2.395

3.  Phenotypic and Genotypic Characterization of Bacteriocinogenic Enterococci Against Clostridium botulinum.

Authors:  Awad A Shehata; Reda Tarabees; Shereen Basiouni; Mahmoud Gamil; Ahmed S Kamal; Monika Krüger
Journal:  Probiotics Antimicrob Proteins       Date:  2017-06       Impact factor: 4.609

4.  Humoral Response of Buffaloes to a Recombinant Vaccine against Botulism Serotypes C and D.

Authors:  Denis Y Otaka; José D Barbosa; Clóvis Moreira; Marcos R A Ferreira; Carlos E P Cunha; Antônio R S Brito; Rafael A Donassolo; Ângela N Moreira; Fabrício R Conceição; Felipe M Salvarani
Journal:  Toxins (Basel)       Date:  2017-09-22       Impact factor: 4.546

5.  Genomic analysis of endemic clones of toxigenic and non-toxigenic Corynebacterium diphtheriae in Belarus during and after the major epidemic in 1990s.

Authors:  Steffen Grosse-Kock; Valentina Kolodkina; Edward C Schwalbe; Jochen Blom; Andreas Burkovski; Paul A Hoskisson; Sylvain Brisse; Darren Smith; Iain C Sutcliffe; Leonid Titov; Vartul Sangal
Journal:  BMC Genomics       Date:  2017-11-13       Impact factor: 3.969

Review 6.  Vaccine Production to Protect Animals Against Pathogenic Clostridia.

Authors:  Nicolas E Zaragoza; Camila A Orellana; Glenn A Moonen; George Moutafis; Esteban Marcellin
Journal:  Toxins (Basel)       Date:  2019-09-11       Impact factor: 4.546

7.  More than a Toxin: Protein Inventory of Clostridium tetani Toxoid Vaccines.

Authors:  Jens Möller; Max Edmund Kraner; Andreas Burkovski
Journal:  Proteomes       Date:  2019-04-16

Review 8.  Major pathogenic Clostridia in human and progress toward the clostridial vaccines.

Authors:  Lida Abdolmohammadi Khiav; Azadeh Zahmatkesh
Journal:  Iran J Basic Med Sci       Date:  2022-09       Impact factor: 2.532

Review 9.  Vaccines against Botulism.

Authors:  Grace Sundeen; Joseph T Barbieri
Journal:  Toxins (Basel)       Date:  2017-09-02       Impact factor: 4.546
  9 in total

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