| Literature DB >> 238316 |
G Schmidt, R D Walter, E Königk.
Abstract
A purine nucleoside hydrolase from Trypanosoma gambiense was purified 160-fold. Preferred substrates of the reaction were adenosine, inosine and guanosine with a maximum of activity at pH 5.4. Competitive inhibitors of the adenosine hydrolysis were dimethylallyl adenosine, 6-methylmercaptopurine riboside, tubercidin, formycin B, 6-mercaptopurine riboside and deoxyadenosine. A metabolic scheme of adenosine nomophosphate salvage synthesis is discussed.Entities:
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Year: 1975 PMID： 238316
Source DB: PubMed Journal: Tropenmed Parasitol ISSN： 0303-4208