Literature DB >> 23828656

Synthesis and Properties of Disulfide-Bond Containing Eight-Membered Rings.

Erik L Ruggles1, Robert J Hondal.   

Abstract

The cyclocystine ring structure (CRS, 3), which results from a disulfide-bond between adjacent cysteine residues, is a rare motif in protein structures and is functionally important to those few proteins that posses it. This communication will focus on the construction of CRS mimics and the determination of their respective redox potentials.

Entities:  

Keywords:  cyclocystine; dithiocine; thiol-disulfide redox; vicinal disulfide-bond

Year:  2006        PMID： 23828656      PMCID： PMC3698869          DOI： 10.1016/j.tetlet.2006.04.023

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN： 0040-4039            Impact factor:   2.415


  6 in total

1.  A versatile indium trichloride mediated Prins-type reaction to unsaturated heterocycles.

Authors:  Adrian P Dobbs; Sebastien J J Guesné; Sasa Martinović; Simon J Coles; Michael B Hursthouse
Journal:  J Org Chem       Date:  2003-10-03       Impact factor: 4.354

2.  Disulfide-strapped porphyrins for monolayer formation on gold

Authors: 
Journal:  Org Lett       Date:  2000-12-28       Impact factor: 6.005

3.  Three-dimensional structure of a mammalian thioredoxin reductase: implications for mechanism and evolution of a selenocysteine-dependent enzyme.

Authors:  T Sandalova; L Zhong; Y Lindqvist; A Holmgren; G Schneider
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-31       Impact factor: 11.205

4.  Dependence of formation of small disulfide loops in two-cysteine peptides on the number and types of intervening amino acids.

Authors:  R M Zhang; G H Snyder
Journal:  J Biol Chem       Date:  1989-11-05       Impact factor: 5.157

Review 5.  Vicinal disulfide turns.

Authors:  Oliviero Carugo; Masa Cemazar; Sotir Zahariev; Ilona Hudáky; Zoltán Gáspári; András Perczel; Sándor Pongor
Journal:  Protein Eng       Date:  2003-09

6.  Vicinal disulfide bridge conformers by experimental methods and by ab initio and DFT molecular computations.

Authors:  Ilona Hudáky; Zoltán Gáspári; Oliviero Carugo; Masa Cemazar; Sándor Pongor; András Perczel
Journal:  Proteins       Date:  2004-04-01
  6 in total
  3 in total

1.  Synthesis, Redox Properties, and Conformational Analysis of Vicinal Disulfide Ring Mimics.

Authors:  Erik L Ruggles; P Bruce Deker; Robert J Hondal
Journal:  Tetrahedron       Date:  2009-02-14       Impact factor: 2.457

2.  A viable synthesis of N-methyl cysteine.

Authors:  Erik L Ruggles; Stevenson Flemer; Robert J Hondal
Journal:  Biopolymers       Date:  2008       Impact factor: 2.505

3.  Synthesis of peptide substrates for mammalian thioredoxin reductase.

Authors:  Stevenson Flemer; Brian M Lacey; Robert J Hondal
Journal:  J Pept Sci       Date:  2008-05       Impact factor: 1.905
  3 in total

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