| Literature DB >> 23827328 |
Sabine Flommersfeld1, Tamam Bakchoul, Gregor Bein, Almut Wachtel, Cordula Loechelt, Ulrich J Sachs.
Abstract
Three different apheresis systems were used in our center for the collection of peripheral blood progenitor cells (PBPCs): COM.TEC (Fresenius Healthcare), COBE Spectra, and Spectra Optia (both from Caridian BCT). We compared 131 autologous and 56 allogeneic apheresis procedures to elucidate feasibility and effectiveness of the different systems. Collection efficiacy varied significantly with lowest results obtained with COBE Spectra. COM.TEC and Spectra Optia produced lower WBC contamination than COBE Spectra, but at the expense of higher product volume and longer apheresis time. High collection efficacy and a low product volume may be favorable characteristics of the Spectra Optia.Keywords: Apheresis procedures; BW; CE; CR; Collection efficacy; G-CSF; Granulocyte-Colony Stimulating Factor; NHL; Non-Hodgkin lymphoma; PBPCs; PLT; Platelet; Stem cell collection; TPV; Total processed volume; WBC; White Blood Count; body weight; collection efficacy; collection rate; peripheral blood progenitor cells
Mesh：
Year: 2013 PMID： 23827328 DOI： 10.1016/j.transci.2013.06.002
Source DB: PubMed Journal: Transfus Apher Sci ISSN： 1473-0502 Impact factor: 1.764