Literature DB >> 23827164

Bath salts intoxication: a case series.

Syed F Imam1, Hetalben Patel, Monay Mahmoud, Nisha A Prakash, Matthew S King, Richard D Fremont.   

Abstract

BACKGROUND: Bath salts commonly contain multiple synthetic drugs, and their toxic effects are largely the same as those seen in patients who have taken large doses of amphetamines. Bath salts can be ingested, smoked, or administered intravenously. Their use is on the rise and is responsible for a large number of emergency department visits. CASE REPORT: Our case series involved five patients (six hospital courses) who presented after ingesting bath salts. The presentations involved signs and symptoms of intense sympathetic response. All patients had a history of drug abuse, and most had psychiatric disorders as well. Treatments included benzodiazepines, mechanical ventilation, and intravenous hydration.
CONCLUSION: Bath salts are available for approximately $20 (USD) in packets at truck stops and on the Internet, usually marketed with the disclaimer, "not for human consumption." Their presentation mimics other sympathetic drugs and causes a significant amount of delirium, hallucinogenic-delusional symptoms, extreme agitation, combativeness, and rhabdomyolysis, often leading to hospitalizations and intensive care unit (ICU) stays. Management is largely supportive and includes aggressive intravenous hydration, dampening of the excessive sympathetic outflow with benzodiazepines, and close monitoring in the ICU setting. The U.S. Drug Enforcement Administration (DEA) recently invoked its emergency scheduling authority to control these synthetic stimulants. The DEA plans to make possessing and selling these chemicals, or products that contain them, illegal in the United States.
Copyright © 2013 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Bliss; Ivory Wave; Vanilla Sky; agitated delirium; bath salts; mephedrone; stimulant overdoses; toxicology

Mesh:

Substances:

Year:  2013        PMID: 23827164     DOI: 10.1016/j.jemermed.2013.04.017

Source DB:  PubMed          Journal:  J Emerg Med        ISSN: 0736-4679            Impact factor:   1.484


  4 in total

1.  Low-normal doses of methiopropamine induce aggressive behaviour in mice.

Authors:  Federica Foti; Sabrine Bilel; Fabio De-Giorgio; Matteo Marti; Micaela Tirri; Raffaella Arfè; Federica Boccuto; Tatiana Bernardi; Giovanni Serpelloni
Journal:  Psychopharmacology (Berl)       Date:  2021-03-26       Impact factor: 4.530

2.  The clinical challenges of synthetic cathinones.

Authors:  Fabrizio Schifano; Flavia Napoletano; Davide Arillotta; Caroline Zangani; Liam Gilgar; Amira Guirguis; John Martin Corkery; Alessandro Vento
Journal:  Br J Clin Pharmacol       Date:  2020-02-03       Impact factor: 4.335

3.  The Designer Drug 3-Fluoromethcathinone Induces Oxidative Stress and Activates Autophagy in HT22 Neuronal Cells.

Authors:  Kamila Siedlecka-Kroplewska; Agata Wrońska; Grzegorz Stasiłojć; Zbigniew Kmieć
Journal:  Neurotox Res       Date:  2018-04-14       Impact factor: 3.911

Review 4.  The role of restraint in fatal excited delirium: a research synthesis and pooled analysis.

Authors:  Ellen M F Strömmer; Wendy Leith; Maurice P Zeegers; Michael D Freeman
Journal:  Forensic Sci Med Pathol       Date:  2020-08-22       Impact factor: 2.007

  4 in total

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