Literature DB >> 23826878

Tuberculosis patients hospitalized in the Albert Schweitzer Hospital, Lambaréné, Gabon-a retrospective observational study.

S M Stolp1, M A M Huson, S Janssen, J O Beyeme, M P Grobusch.   

Abstract

Epidemiological data on tuberculosis in Central Africa are limited. We performed a retrospective observational study on clinical characteristics of 719 hospitalized tuberculosis patients in Lambaréné, Gabon. Human immunodeficiency virus (HIV) co-infection rate was high (34%) and in-hospital mortality was significantly higher in HIV-positive patients (10% versus 2%). Long-term information on patient outcome was limited; however, from 2008 to 2011, loss to follow up was noted in 28% of cases. Our data illustrate the high burden of TB in Gabon, where loss to follow up and emerging drug resistance are important problems for which comprehensive data are still lacking.
© 2013 The Authors Clinical Microbiology and Infection © 2013 European Society of Clinical Microbiology and Infectious Diseases.

Entities:  

Keywords:  Central Africa; Gabon; drug resistance; human immunodeficiency virus; tuberculosis

Mesh：

Year:  2013        PMID： 23826878     DOI： 10.1111/1469-0691.12278

Source DB:  PubMed          Journal:  Clin Microbiol Infect        ISSN： 1198-743X            Impact factor:   8.067


  7 in total

1.  Tuberculosis Treatment Outcome and Drug Resistance in Lambaréné, Gabon: A Prospective Cohort Study.

Authors:  Sabine Bélard; Jonathan Remppis; Sanne Bootsma; Saskia Janssen; Davy U Kombila; Justin O Beyeme; Elie G Rossatanga; Cosme Kokou; Kara K Osbak; Régis M Obiang Mba; Harry M Kaba; Afsatou N Traoré; Jonas Ehrhardt; Emmanuel B Bache; Arnaud Flamen; Sabine Rüsch-Gerdes; Matthias Frank; Ayôla A Adegnika; Bertrand Lell; Stefan Niemann; Peter G Kremsner; Marguerite M Loembé; Abraham S Alabi; Martin P Grobusch
Journal:  Am J Trop Med Hyg       Date:  2016-06-27       Impact factor: 2.345

Review 2.  Methicillin-resistant Staphylococcus aureus as a cause of invasive infections in Central Africa: a case report and review of the literature.

Authors:  M A M Huson; R Kalkman; J Remppis; J O Beyeme; C Kraef; F Schaumburg; A S Alabi; M P Grobusch
Journal:  Infection       Date:  2014-01-25       Impact factor: 3.553

3.  The impact of HIV on presentation and outcome of bacterial sepsis and other causes of acute febrile illness in Gabon.

Authors:  Michaëla A M Huson; Rachel Kalkman; Sebastiaan M Stolp; Saskia Janssen; Abraham S Alabi; Justin O Beyeme; Tom van der Poll; Martin P Grobusch
Journal:  Infection       Date:  2015-03-11       Impact factor: 3.553

4.  Low incidence of the immune reconstitution inflammatory syndrome among HIV-infected patients starting antiretroviral therapy in Gabon: a prospective cohort study.

Authors:  S Janssen; K Osbak; R Holman; S Hermans; A Moekotte; M Knap; E Rossatanga; M Massinga-Loembe; A Alabi; A Adegnika; C Meenken; M van Vugt; P G Kremsner; G Meintjes; T van der Poll; M P Grobusch
Journal:  Infection       Date:  2017-03-27       Impact factor: 3.553

5.  Use of GeneXpert Remnants for Drug Resistance Profiling and Molecular Epidemiology of Tuberculosis in Libreville, Gabon.

Authors:  Amel Kévin Alame-Emane; Catherine Pierre-Audigier; Oriane Cordelia Aboumegone-Biyogo; Amandine Nzoghe-Mveang; Véronique Cadet-Daniel; Christophe Sola; Joël Fleury Djoba-Siawaya; Brigitte Gicquel; Howard E Takiff
Journal:  J Clin Microbiol       Date:  2017-04-26       Impact factor: 5.948

Review 6.  Prevalence of extrapulmonary tuberculosis among people living with HIV/AIDS in sub-Saharan Africa: a systemic review and meta-analysis.

Authors:  Hussen Mohammed; Nega Assefa; Bezatu Mengistie
Journal:  HIV AIDS (Auckl)       Date:  2018-11-05

Review 7.  Development of sustainable research excellence with a global perspective on infectious diseases: Centre de Recherches Médicales de Lambaréné (CERMEL), Gabon.

Authors:  Michael Ramharter; Selidji T Agnandji; Ayôla A Adegnika; Bertrand Lell; Ghyslain Mombo-Ngoma; Martin P Grobusch; Matthew McCall; Riko Muranaka; Andrea Kreidenweiss; Thirumalaisamy P Velavan; Meral Esen; Frieder Schaumburg; Abraham Alabi; Christiane Druml; Benjamin Mordmüller; Carsten Köhler; Peter G Kremsner
Journal:  Wien Klin Wochenschr       Date:  2021-01-04       Impact factor: 1.704
  7 in total

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