Literature DB >> 23826536

Forty-five years of keratoprosthesis study and application at the Filatov Institute: a retrospective analysis of 1 060 cases.

Stanislav Iakymenko1.   

Abstract

AIM: To present results of the keratoprosthesis method used at The Filatov Institute of Eye Diseases and Tissue Therapy.
METHODS: A retrospective case series analysis was used to describe the development of new types of keratoprostheses and methods of implantation as well as different ways of leukoma strengthening.
RESULTS: Keratoprosthesis was performed in 1 060 eyes of 1 040 patients with leukomas of different etiology: burns, 725 eyes (68.4%); trauma, 120 eyes (11.3%); keratitis and ocular pemphigoid, 108 eyes (10.2%); and bullous keratopathy, 107 eyes (10.1%). Visual acuity before keratoprosthesis consisted of light perception in 962 eyes (92%), and 98 eyes (8%) had minimal visual acuity (1/200-1/50). Both eyes were blind (visual acuity less than 1/200) in 955 patients (91.8%). The period of blindness varied from 1 to 52 years. As a result of keratoprosthesis, visual acuity of ≥1/200 was restored in 1 023 of 1 060 eyes (96.5%). Visual acuity of 20/200-20/20 was achieved in 716 eyes (67.5%). At the last follow-up visit visual acuity of ≥1/200 was preserved in 806 eyes (76%), visual acuity of 20/200-20/20 was measured in 583 of 1 060 eyes (55%) and good keratoprosthesis fixation in the cornea was achieved in 986 of 1 060 eyes (93%). The minimal follow-up was 12 months (range, 12 months to 37 years, median 5 years).
CONCLUSION: Our techniques of keratoprosthesis effectively restore vision in patients with leukomas that cannot be treated by optical corneal grafting.

Entities:  

Keywords:  artificial cornea; corneal grafting; keratoprosthesis; leukoma

Year:  2013        PMID: 23826536      PMCID: PMC3693023          DOI: 10.3980/j.issn.2222-3959.2013.03.22

Source DB:  PubMed          Journal:  Int J Ophthalmol        ISSN: 2222-3959            Impact factor:   1.779


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10.  Regeneration of corneal cells and nerves in an implanted collagen corneal substitute.

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Authors:  Anahita Kate; Sayan Basu
Journal:  Front Med (Lausanne)       Date:  2022-05-25

2.  Temporary Kerato-Prosthesis to Resolve Traumatic Loss of a Healed Corneal Button.

Authors:  Alessandra Balestrazzi; Alessandro Di Maggio; Paolo Michieletto; Gianluca Martone; Angelo Balestrazzi
Journal:  Case Rep Ophthalmol       Date:  2021-04-16

Review 3.  Keratoprostheses for corneal blindness: a review of contemporary devices.

Authors:  Venkata S Avadhanam; Helen E Smith; Christopher Liu
Journal:  Clin Ophthalmol       Date:  2015-04-16
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