Literature DB >> 23825192

Demonstrated efficacy of a pilot heterologous whole-spore vaccine against Microsporidial gill disease in rainbow trout.

J E Harkness1, N J Guselle, D J Speare.   

Abstract

Intraperitoneal vaccines using whole viable spores of the microsporidian Glugea anomala or Glugea hertwigi reduced the numbers of branchial xenomas by 80% and 91%, respectively, after a standard experimental infection of juvenile rainbow trout with the microsporidian Loma salmonae. Similar significant results were obtained when killed-spore preparations were used.

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Year:  2013        PMID： 23825192      PMCID： PMC3889595          DOI： 10.1128/CVI.00340-13

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


  5 in total

1.  Cellular immunity in salmonids infected with the microsporidial parasite Loma salmonae or exposed to non-viable spores.

Authors:  L E Rodriguez-Tovar; R J F Markham; D J Speare; J Sheppard
Journal:  Vet Immunol Immunopathol       Date:  2006-08-23       Impact factor: 2.046

Review 2.  Review of the sequential development of Loma salmonae (Microsporidia) based on experimental infections of rainbow trout (Oncorhynchus mykiss) and Chinook salmon (O. tshawytscha).

Authors:  Michael L Kent; David J Speare
Journal:  Folia Parasitol (Praha)       Date:  2005-05       Impact factor: 2.122

3.  Acute and long-term humoral immunity following active immunization of rabbits with inactivated spores of various Encephalitozoon species.

Authors:  I Sobottka; F Iglauer; T Schüler; C Schmetz; G S Visvesvara; H Albrecht; D A Schwartz; N J Pieniazek; K Bartscht; R Laufs; J Schottelius
Journal:  Parasitol Res       Date:  2001-01       Impact factor: 2.289

4.  Development of an effective whole-spore vaccine to protect against microsporidial gill disease in rainbow trout (Oncorhynchus mykiss) by using a low-virulence strain of Loma salmonae.

Authors:  D J Speare; R J F Markham; N J Guselle
Journal:  Clin Vaccine Immunol       Date:  2007-10-17

5.  Phylogeny and morphology of Glugea hertwigi from rainbow smelt Osmerus mordax found in Prince Edward Island, Canada.

Authors:  J Lovy; M Kostka; I Dyková; G Arsenault; H Pecková; G M Wright; D J Speare
Journal:  Dis Aquat Organ       Date:  2009-11-09       Impact factor: 1.802
  5 in total
  1 in total

Review 1.  Microsporidia-host interactions.

Authors:  Suzannah C Szumowski; Emily R Troemel
Journal:  Curr Opin Microbiol       Date:  2015-04-04       Impact factor: 7.934
  1 in total

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