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Literature DB >> 23823660

Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies.

J A Oyer¹, X Huang², Y Zheng³, J Shim⁴, T Ezponda¹, Z Carpenter⁵, M Allegretta⁵, C I Okot-Kotber¹, J P Patel⁶, A Melnick⁷, R L Levine⁶, A Ferrando⁵, A D Mackerell⁴, N L Kelleher³, J D Licht¹, R Popovic¹.

Abstract

Entities: CellLine Chemical Disease Gene Mutation Species

Mesh：

Substances：

Year: 2013 PMID： 23823660 PMCID： PMC3888226 DOI： 10.1038/leu.2013.204

Source DB: PubMed Journal: Leukemia ISSN： 0887-6924 Impact factor: 11.528

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15 in total

1. The structure of NSD1 reveals an autoregulatory mechanism underlying histone H3K36 methylation.

Authors: Qi Qiao; Yan Li; Zhi Chen; Mingzhu Wang; Danny Reinberg; Rui-Ming Xu
Journal: J Biol Chem Date: 2010-12-31 Impact factor: 5.157

2. The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells.

Authors: Eva Martinez-Garcia; Relja Popovic; Dong-Joon Min; Steve M M Sweet; Paul M Thomas; Leonid Zamdborg; Aaron Heffner; Christine Will; Laurence Lamy; Louis M Staudt; David L Levens; Neil L Kelleher; Jonathan D Licht
Journal: Blood Date: 2010-10-25 Impact factor: 22.113

3. H3K36 methylation antagonizes PRC2-mediated H3K27 methylation.

Authors: Wen Yuan; Mo Xu; Chang Huang; Nan Liu; She Chen; Bing Zhu
Journal: J Biol Chem Date: 2011-01-14 Impact factor: 5.157

4. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.

Authors: Jinghui Zhang; Li Ding; Linda Holmfeldt; Gang Wu; Sue L Heatley; Debbie Payne-Turner; John Easton; Xiang Chen; Jianmin Wang; Michael Rusch; Charles Lu; Shann-Ching Chen; Lei Wei; J Racquel Collins-Underwood; Jing Ma; Kathryn G Roberts; Stanley B Pounds; Anatoly Ulyanov; Jared Becksfort; Pankaj Gupta; Robert Huether; Richard W Kriwacki; Matthew Parker; Daniel J McGoldrick; David Zhao; Daniel Alford; Stephen Espy; Kiran Chand Bobba; Guangchun Song; Deqing Pei; Cheng Cheng; Stefan Roberts; Michael I Barbato; Dario Campana; Elaine Coustan-Smith; Sheila A Shurtleff; Susana C Raimondi; Maria Kleppe; Jan Cools; Kristin A Shimano; Michelle L Hermiston; Sergei Doulatov; Kolja Eppert; Elisa Laurenti; Faiyaz Notta; John E Dick; Giuseppe Basso; Stephen P Hunger; Mignon L Loh; Meenakshi Devidas; Brent Wood; Stuart Winter; Kimberley P Dunsmore; Robert S Fulton; Lucinda L Fulton; Xin Hong; Christopher C Harris; David J Dooling; Kerri Ochoa; Kimberly J Johnson; John C Obenauer; William E Evans; Ching-Hon Pui; Clayton W Naeve; Timothy J Ley; Elaine R Mardis; Richard K Wilson; James R Downing; Charles G Mullighan
Journal: Nature Date: 2012-01-11 Impact factor: 49.962

5. The histone methyltransferase and putative oncoprotein MMSET is overexpressed in a large variety of human tumors.

Authors: Heidi Rye Hudlebusch; Eric Santoni-Rugiu; Ronald Simon; Elisabeth Ralfkiær; Henrik Holm Rossing; Jens Vilstrup Johansen; Mette Jørgensen; Guido Sauter; Kristian Helin
Journal: Clin Cancer Res Date: 2011-03-08 Impact factor: 12.531

Review 6. Acute lymphoblastic leukaemia.

Authors: Hiroto Inaba; Mel Greaves; Charles G Mullighan
Journal: Lancet Date: 2013-03-22 Impact factor: 79.321

7. Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation.

Authors: Giulia Fabbri; Silvia Rasi; Davide Rossi; Vladimir Trifonov; Hossein Khiabanian; Jing Ma; Adina Grunn; Marco Fangazio; Daniela Capello; Sara Monti; Stefania Cresta; Ernesto Gargiulo; Francesco Forconi; Anna Guarini; Luca Arcaini; Marco Paulli; Luca Laurenti; Luigi M Larocca; Roberto Marasca; Valter Gattei; David Oscier; Francesco Bertoni; Charles G Mullighan; Robin Foá; Laura Pasqualucci; Raul Rabadan; Riccardo Dalla-Favera; Gianluca Gaidano
Journal: J Exp Med Date: 2011-06-13 Impact factor: 14.307

8. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Authors: Jordi Barretina; Giordano Caponigro; Nicolas Stransky; Kavitha Venkatesan; Adam A Margolin; Sungjoon Kim; Christopher J Wilson; Joseph Lehár; Gregory V Kryukov; Dmitriy Sonkin; Anupama Reddy; Manway Liu; Lauren Murray; Michael F Berger; John E Monahan; Paula Morais; Jodi Meltzer; Adam Korejwa; Judit Jané-Valbuena; Felipa A Mapa; Joseph Thibault; Eva Bric-Furlong; Pichai Raman; Aaron Shipway; Ingo H Engels; Jill Cheng; Guoying K Yu; Jianjun Yu; Peter Aspesi; Melanie de Silva; Kalpana Jagtap; Michael D Jones; Li Wang; Charles Hatton; Emanuele Palescandolo; Supriya Gupta; Scott Mahan; Carrie Sougnez; Robert C Onofrio; Ted Liefeld; Laura MacConaill; Wendy Winckler; Michael Reich; Nanxin Li; Jill P Mesirov; Stacey B Gabriel; Gad Getz; Kristin Ardlie; Vivien Chan; Vic E Myer; Barbara L Weber; Jeff Porter; Markus Warmuth; Peter Finan; Jennifer L Harris; Matthew Meyerson; Todd R Golub; Michael P Morrissey; William R Sellers; Robert Schlegel; Levi A Garraway
Journal: Nature Date: 2012-03-28 Impact factor: 49.962

9. Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer.

Authors: Gijs van Haaften; Gillian L Dalgliesh; Helen Davies; Lina Chen; Graham Bignell; Chris Greenman; Sarah Edkins; Claire Hardy; Sarah O'Meara; Jon Teague; Adam Butler; Jonathan Hinton; Calli Latimer; Jenny Andrews; Syd Barthorpe; Dave Beare; Gemma Buck; Peter J Campbell; Jennifer Cole; Simon Forbes; Mingming Jia; David Jones; Chai Yin Kok; Catherine Leroy; Meng-Lay Lin; David J McBride; Mark Maddison; Simon Maquire; Kirsten McLay; Andrew Menzies; Tatiana Mironenko; Lee Mulderrig; Laura Mudie; Erin Pleasance; Rebecca Shepherd; Raffaella Smith; Lucy Stebbings; Philip Stephens; Gurpreet Tang; Patrick S Tarpey; Rachel Turner; Kelly Turrell; Jennifer Varian; Sofie West; Sara Widaa; Paul Wray; V Peter Collins; Koichi Ichimura; Simon Law; John Wong; Siu Tsan Yuen; Suet Yi Leung; Giovanni Tonon; Ronald A DePinho; Yu-Tzu Tai; Kenneth C Anderson; Richard J Kahnoski; Aaron Massie; Sok Kean Khoo; Bin Tean Teh; Michael R Stratton; P Andrew Futreal
Journal: Nat Genet Date: 2009-03-29 Impact factor: 38.330

10. The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial-mesenchymal transition and invasive properties of prostate cancer.

Authors: T Ezponda; R Popovic; M Y Shah; E Martinez-Garcia; Y Zheng; D-J Min; C Will; A Neri; N L Kelleher; J Yu; J D Licht
Journal: Oncogene Date: 2012-07-16 Impact factor: 9.867

65 in total

Review 1. Histone methyltransferases: novel targets for tumor and developmental defects.

Authors: Xin Yi; Xue-Jun Jiang; Xiao-Yan Li; Ding-Sheng Jiang
Journal: Am J Transl Res Date: 2015-11-15 Impact factor: 4.060

2. Unabridged Analysis of Human Histone H3 by Differential Top-Down Mass Spectrometry Reveals Hypermethylated Proteoforms from MMSET/NSD2 Overexpression.

Authors: Yupeng Zheng; Luca Fornelli; Philip D Compton; Seema Sharma; Jesse Canterbury; Christopher Mullen; Vlad Zabrouskov; Ryan T Fellers; Paul M Thomas; Jonathan D Licht; Michael W Senko; Neil L Kelleher
Journal: Mol Cell Proteomics Date: 2015-08-13 Impact factor: 5.911

Review 3. The Role of Nuclear Receptor-Binding SET Domain Family Histone Lysine Methyltransferases in Cancer.

Authors: Richard L Bennett; Alok Swaroop; Catalina Troche; Jonathan D Licht
Journal: Cold Spring Harb Perspect Med Date: 2017-06-01 Impact factor: 6.915

Review 4. Molecular pathways: deregulation of histone h3 lysine 27 methylation in cancer-different paths, same destination.

Authors: Teresa Ezponda; Jonathan D Licht
Journal: Clin Cancer Res Date: 2014-07-01 Impact factor: 12.531

5. MB4-2 breakpoint in MMSET combined with del(17p) defines a subset of t(4;14) multiple myeloma with very poor prognosis.

Authors: Anne Lazareth; Xiu-Yi Song; Aurelie Coquin; Stephanie Harel; Lionel Karlin; Karim Belhadj; Damien Roos-Weil; Laurent Frenzel; Jerôme Tamburini; Margaret Macro; Sylvie Chevret; Hervé Avet Loiseau; Stephane Minvielle; Jean Paul Fermand; Jean Soulier; Jean Christophe Bories; Bertrand Arnulf
Journal: Haematologica Date: 2015-07-23 Impact factor: 9.941

6. The dynamic conformational landscape of the protein methyltransferase SETD8.

Authors: Shi Chen; Rafal P Wiewiora; Fanwang Meng; Nicolas Babault; Anqi Ma; Wenyu Yu; Kun Qian; Hao Hu; Hua Zou; Junyi Wang; Shijie Fan; Gil Blum; Fabio Pittella-Silva; Kyle A Beauchamp; Wolfram Tempel; Hualiang Jiang; Kaixian Chen; Robert J Skene; Yujun George Zheng; Peter J Brown; Jian Jin; Cheng Luo; John D Chodera; Minkui Luo
Journal: Elife Date: 2019-05-13 Impact factor: 8.140