Effects of whole-body vibration exercise training on aortic wave reflection and muscle strength in postmenopausal women with prehypertension and hypertension.

Increased wave reflection (augmented pressure (AP) and augmentation index (AIx)) and reduced muscle strength may increase cardiovascular risk in postmenopausal women. We evaluated the effects of whole-body vibration exercise training (WBVET) on aortic haemodynamics and leg muscle strength. Twenty-eight postmenopausal women (age, 56±3 years; brachial systolic blood pressure (SBP) 138±12 mm Hg; body mass index, 33.9±3.7 kg m(-2)) were randomized to 6 weeks of WBVET (n=15) or no-exercise control groups. Aortic SBP, diastolic blood pressure (DBP), pulse pressure (PP), AP, AIx, tension time index (TTI, myocardial oxygen demand) and leg press muscle strength were measured before and after 6 weeks. WBVET significantly (P<0.05) decreased aortic SBP (∼10 mm Hg), DBP (∼5 mm Hg), PP (∼5 mm Hg), AP (∼5 mm Hg), AIx (∼10%) and TTI (∼311 mm Hg s per minute), while increased muscle strength (∼9%) compared with no changes after control. Changes in AP and leg muscle strength were correlated (r=-0.58, P=0.02). Our data demonstrated that WBVET reduced pressure wave reflection magnitude and aortic blood pressure in postmenopausal women with prehypertension or hypertension. Our study suggests that WBVET may decrease cardiovascular risk in postmenopausal women by improving wave reflection and muscle strength.

RCT Entities:   Population Interventions Outcomes