Literature DB >> 23823472

Betatrophin fuels β cell proliferation: first step toward regenerative therapy?

Heiko Lickert1.   

Abstract

Millions of diabetic patients are waiting for better treatment options, ideally by replenishing the lost or dysfunctional insulin-producing β cell mass. Yi et al. (2013) now identify Betatrophin, a hormone that specifically increases β cell proliferation with promising therapeutic potential.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID： 23823472     DOI： 10.1016/j.cmet.2013.06.006

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  21 in total

Review 1.  Development, growth and maintenance of β-cell mass: models are also part of the story.

Authors:  Anmar Khadra; Santiago Schnell
Journal:  Mol Aspects Med       Date:  2015-02-23

Review 2.  New insights into ANGPTL8 in modulating the development of cardio-metabolic disorder diseases.

Authors:  Xin Su; Guoming Zhang; Ye Cheng; Bin Wang
Journal:  Mol Biol Rep       Date:  2021-04-17       Impact factor: 2.316

3.  Effect of physical activity in a weight loss program on circulating total ANGPTL8 concentrations in northern Americans with obesity: A prospective randomized controlled trial.

Authors:  Chia-Po Fu; Elizabeth E Oczypok; Hira Ali; James P DeLany; Valerie L Reeves; Ruey-Feng Chang; Erin E Kershaw
Journal:  Nutr Metab Cardiovasc Dis       Date:  2022-04-12       Impact factor: 4.666

4.  The p38-PGC-1α-irisin-betatrophin axis: Exploring new pathways in insulin resistance.

Authors:  Fabian Sanchis-Gomar; Carme Perez-Quilis
Journal:  Adipocyte       Date:  2013-12-11       Impact factor: 4.534

5.  Circulating betatrophin correlates with atherogenic lipid profiles but not with glucose and insulin levels in insulin-resistant individuals.

Authors:  Anna Fenzl; Bianca K Itariu; Lana Kosi; Monika Fritzer-Szekeres; Alexandra Kautzky-Willer; Thomas M Stulnig; Florian W Kiefer
Journal:  Diabetologia       Date:  2014-03-13       Impact factor: 10.122

6.  Angiopoietin-like protein 8 (ANGPTL8)/betatrophin overexpression does not increase beta cell proliferation in mice.

Authors:  Aaron R Cox; Carol J Lam; Claire W Bonnyman; Julia Chavez; Jacqueline S Rios; Jake A Kushner
Journal:  Diabetologia       Date:  2015-04-28       Impact factor: 10.122

7.  Lack of associations between betatrophin/ANGPTL8 level and C-peptide in type 2 diabetic subjects.

Authors:  Mohamed Abu-Farha; Jehad Abubaker; Fiona Noronha; Irina Al-Khairi; Preethi Cherian; Monira Alarouj; Abdullah Bennakhi; Naser Elkum
Journal:  Cardiovasc Diabetol       Date:  2015-08-20       Impact factor: 9.951

8.  Circulating Betatrophin Is Strongly Increased in Pregnancy and Gestational Diabetes Mellitus.

Authors:  Lana Kosi Trebotic; Peter Klimek; Anita Thomas; Anna Fenzl; Karoline Leitner; Stefanie Springer; Florian W Kiefer; Alexandra Kautzky-Willer
Journal:  PLoS One       Date:  2015-09-01       Impact factor: 3.240

9.  Circulating Levels of Betatrophin and Irisin Are Not Associated with Pancreatic β-Cell Function in Previously Diagnosed Type 2 Diabetes Mellitus Patients.

Authors:  Lingshu Wang; Jun Song; Chuan Wang; Peng Lin; Kai Liang; Yu Sun; Tianyi He; Wenjuan Li; Ruxing Zhao; Jun Qin; Yiran Lu; Jinbo Liu; Fuqiang Liu; Xinguo Hou; Li Chen
Journal:  J Diabetes Res       Date:  2015-11-16       Impact factor: 4.011

Review 10.  Islet cell plasticity and regeneration.

Authors:  Adriana Migliorini; Erik Bader; Heiko Lickert
Journal:  Mol Metab       Date:  2014-01-22       Impact factor: 7.422
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