| Literature DB >> 23823016 |
Taro Isobe1, Kousuke Hashimoto, Junya Kizaki, Motoshi Miyagi, Keishiro Aoyagi, Kikuo Koufuji, Kazuo Shirouzu.
Abstract
Many elderly individuals suffer from reduced functioning of major organs with cardiovascular and respiratory system comorbidity. Consequently, surgical stress and postoperative complications can be fatal. We investigated whether gastrectomy can safely improve the prognosis in very elderly (>85 years) patients with gastric cancer. We compared the clinical and pathological features of patients 85 years and older (Group A) with those 80- to 84-year-old (Group B) who underwent gastrectomy. We also compared the survival rates of Group A and Group B, and investigated the prognostic factors. Group A had a high incidence of patients with 3 or more comorbidities, but these did not influence postoperative complications or survival rate. Patients at stage I or II had a significantly higher survival rate than those who did not undergo surgery. However, there was no statistical difference in survival rate at stage III or IV. Our study results revealed that in the early stages (I and II) of well-differentiated gastric cancer with low risk of lymph node metastasis, surgery should consist of minimal lymphadenectomy and be minimally invasive. Further, treatments other than gastrectomy should be considered for patients in whom complete resection via reduction surgery is not possible.Entities:
Mesh:
Year: 2012 PMID: 23823016 DOI: 10.2739/kurumemedj.59.61
Source DB: PubMed Journal: Kurume Med J ISSN: 0023-5679