Literature DB >> 238225

Isolation and structure assignment of an antimicrobial principle from the volatile oil of Nigella sativa L. seeds.

H M El-Fatatry.   

Abstract

Refrigeration of the volatile oil of Nigella sativa L. seeds eventuates in a crystalline substance. The chemical structure of the compound was drawn from its chemical behaviour, as well as from its UV, IR, PMR and mass spectral data. The compound was found to be thymohydroquinone: confirmation of the structure was established via the preparation of its corresponding diacetate ester. The compound was found to have high antimicrobial effect against gram positive microorganisms

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Year:  1975        PMID： 238225

Source DB:  PubMed          Journal:  Pharmazie        ISSN： 0031-7144            Impact factor:   1.267


  10 in total

1.  Protective effects of thymoquinone against cholestatic oxidative stress and hepatic damage after biliary obstruction in rats.

Authors:  Serhat Oguz; Mehmet Kanter; Mustafa Erboga; Cengiz Erenoglu
Journal:  J Mol Histol       Date:  2012-01-21       Impact factor: 2.611

2.  Protective effects of thymoquinone on the neuronal injury in frontal cortex after chronic toluene exposure.

Authors:  Mehmet Kanter
Journal:  J Mol Histol       Date:  2010-12-01       Impact factor: 2.611

3.  Detection of the antibacterial effect of Nigella sativa ground seeds with water.

Authors:  Hussein Ahmed Bakathir; Nageeb Ahmed Abbas
Journal:  Afr J Tradit Complement Altern Med       Date:  2010-12-30

4.  Potentiation of Valproate-induced Anticonvulsant Response by Nigella sativa Seed Constituents: The Role of GABA Receptors.

Authors:  Muhammad Raza; Abdullah A Alghasham; Mohammad S Alorainy; Tarig M El-Hadiyah
Journal:  Int J Health Sci (Qassim)       Date:  2008-01

5.  Chemical composition and medicinal properties of Nigella sativa Linn.

Authors:  M A Khan
Journal:  Inflammopharmacology       Date:  1999       Impact factor: 4.473

6.  Synergistic efficacies of thymoquinone and standard antibiotics against multi-drug resistant isolates.

Authors:  Ayed A Dera; Irfan Ahmad; Prasanna Rajagopalan; Mesfer Al Shahrani; Ahmed Saif; Mohammad Y Alshahrani; Yasser Alraey; Ahmad M Alamri; Sultan Alasmari; Mohammed Makkawi; Ali G Alkhathami; Gaffar Zaman; Abdulrahim Hakami; Razan Alhefzi; Mohammad A Alfhili
Journal:  Saudi Med J       Date:  2021-02       Impact factor: 1.484

7.  Antibacterial activity of Thymoquinone, an active principle of Nigella sativa and its potency to prevent bacterial biofilm formation.

Authors:  Kamel Chaieb; Bochra Kouidhi; Hanene Jrah; Kacem Mahdouani; Amina Bakhrouf
Journal:  BMC Complement Altern Med       Date:  2011-04-13       Impact factor: 3.659

8.  Composition, in vitro antioxidant and antimicrobial activities of essential oil and oleoresins obtained from black cumin seeds (Nigella sativa L.).

Authors:  Sunita Singh; S S Das; G Singh; Carola Schuff; Marina P de Lampasona; César A N Catalán
Journal:  Biomed Res Int       Date:  2014-02-06       Impact factor: 3.411

9.  Rhipicephalus annulatus (Acari: Ixodidae) Control by Nigella sativa, Thyme and Spinosad Preparations.

Authors:  Shawky Mohamed Aboelhadid; Hesham A Mahran; Hazem M El-Hariri; Khalid Mohamed Shokier
Journal:  J Arthropod Borne Dis       Date:  2016-01-05       Impact factor: 1.198

10.  An active principle of Nigella sativa L., thymoquinone, showing significant antimicrobial activity against anaerobic bacteria.

Authors:  Mohammad Akram Randhawa; Awwad Khalaf Alenazy; Majed Gorayan Alrowaili; Jamith Basha
Journal:  J Intercult Ethnopharmacol       Date:  2016-11-21
  10 in total

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