Literature DB >> 23822153

MicroRNA in Alzheimer's disease: an exploratory study in brain, cerebrospinal fluid and plasma.

Lynn M Bekris1, Franziska Lutz, Thomas J Montine, Chang En Yu, Debby Tsuang, Elaine R Peskind, James B Leverenz.   

Abstract

MicroRNA (miRNA) may be potential biomarkers of Alzheimer's disease (AD). The objective of this investigation was to demonstrate that miRNAs in human brain or biofluids are differentially expressed according to disease status, tissue type, neuritic plaque score or Braak stage. Post-mortem brain (PMB) miRNA were profiled using arrays and validated using quantitative RT-PCR (qRT-PCR). Five qRT-PCR-validated miRNAs were measured in an independent sample of PMB, cerebrospinal fluid and plasma from the same subjects. Plasma miR-15a was found to be associated with plaque score in the independent sample. In conclusion, miRNA present in human biofluids may offer utility as biomarkers of AD.

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Year:  2013        PMID： 23822153      PMCID： PMC3967870          DOI： 10.3109/1354750X.2013.814073

Source DB:  PubMed          Journal:  Biomarkers        ISSN： 1354-750X            Impact factor:   2.658


  79 in total

Review 1.  MicroRNAs in Alzheimer's disease.

Authors:  Charlotte Delay; Wim Mandemakers; Sébastien S Hébert
Journal:  Neurobiol Dis       Date:  2012-01-17       Impact factor: 5.996

2.  Recent clinical-pathologic research on the causes of dementia in late life: update from the Honolulu-Asia Aging Study.

Authors:  Lon White; Brent J Small; Helen Petrovitch; G Webster Ross; Kamal Masaki; Robert D Abbott; John Hardman; Daron Davis; James Nelson; William Markesbery
Journal:  J Geriatr Psychiatry Neurol       Date:  2005-12       Impact factor: 2.680

Review 3.  The complexities of microRNA regulation: mirandering around the rules.

Authors:  Kimberly Breving; Aurora Esquela-Kerscher
Journal:  Int J Biochem Cell Biol       Date:  2009-09-30       Impact factor: 5.085

4.  microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus.

Authors:  Stephen T Magill; Xiaolu A Cambronne; Bryan W Luikart; Daniel T Lioy; Barbara H Leighton; Gary L Westbrook; Gail Mandel; Richard H Goodman
Journal:  Proc Natl Acad Sci U S A       Date:  2010-11-08       Impact factor: 11.205

Review 5.  Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. The National Institute on Aging, and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease.

Authors: 
Journal:  Neurobiol Aging       Date:  1997 Jul-Aug       Impact factor: 4.673

6.  MicroRNA-298 and microRNA-328 regulate expression of mouse beta-amyloid precursor protein-converting enzyme 1.

Authors:  Vincent Boissonneault; Isabelle Plante; Serge Rivest; Patrick Provost
Journal:  J Biol Chem       Date:  2008-11-05       Impact factor: 5.157

7.  The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia.

Authors:  Ulf Klein; Marie Lia; Marta Crespo; Rachael Siegel; Qiong Shen; Tongwei Mo; Alberto Ambesi-Impiombato; Andrea Califano; Anna Migliazza; Govind Bhagat; Riccardo Dalla-Favera
Journal:  Cancer Cell       Date:  2010-01-07       Impact factor: 31.743

Review 8.  MicroRNAs (miRNAs) in neurodegenerative diseases.

Authors:  Peter T Nelson; Wang-Xia Wang; Bernard W Rajeev
Journal:  Brain Pathol       Date:  2008-01       Impact factor: 6.508

9.  A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis.

Authors:  Gabriele Siegel; Gregor Obernosterer; Roberto Fiore; Martin Oehmen; Silvia Bicker; Mette Christensen; Sharof Khudayberdiev; Philipp F Leuschner; Clara J L Busch; Christina Kane; Katja Hübel; Frank Dekker; Christian Hedberg; Balamurugan Rengarajan; Carsten Drepper; Herbert Waldmann; Sakari Kauppinen; Michael E Greenberg; Andreas Draguhn; Marc Rehmsmeier; Javier Martinez; Gerhard M Schratt
Journal:  Nat Cell Biol       Date:  2009-05-24       Impact factor: 28.824

10.  The microRNA.org resource: targets and expression.

Authors:  Doron Betel; Manda Wilson; Aaron Gabow; Debora S Marks; Chris Sander
Journal:  Nucleic Acids Res       Date:  2007-12-23       Impact factor: 16.971
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  45 in total

1.  Effects of aging on circadian patterns of gene expression in the human prefrontal cortex.

Authors:  Cho-Yi Chen; Ryan W Logan; Tianzhou Ma; David A Lewis; George C Tseng; Etienne Sibille; Colleen A McClung
Journal:  Proc Natl Acad Sci U S A       Date:  2015-12-22       Impact factor: 11.205

2.  Plasma miR-34a-5p and miR-545-3p as Early Biomarkers of Alzheimer's Disease: Potential and Limitations.

Authors:  Marta Cosín-Tomás; Anna Antonell; Albert Lladó; Daniel Alcolea; Juan Fortea; Mario Ezquerra; Albert Lleó; Maria José Martí; Mercè Pallàs; Raquel Sanchez-Valle; José Luís Molinuevo; Coral Sanfeliu; Perla Kaliman
Journal:  Mol Neurobiol       Date:  2016-09-08       Impact factor: 5.590

Review 3.  Exploring Biomarkers for Alzheimer's Disease.

Authors:  Neeti Sharma; Anshika Nikita Singh
Journal:  J Clin Diagn Res       Date:  2016-07-01

Review 4.  Role of viruses, prions and miRNA in neurodegenerative disorders and dementia.

Authors:  Sayed Sartaj Sohrab; Mohd Suhail; Ashraf Ali; Mohammad Amjad Kamal; Azamal Husen; Fahim Ahmad; Esam Ibraheem Azhar; Nigel H Greig
Journal:  Virusdisease       Date:  2018-09-29

Review 5.  Are microRNAs the Molecular Link Between Metabolic Syndrome and Alzheimer's Disease?

Authors:  Juan F Codocedo; Juvenal A Ríos; Juan A Godoy; Nibaldo C Inestrosa
Journal:  Mol Neurobiol       Date:  2015-05-15       Impact factor: 5.590

6.  The Influence of Extracellular RNA on Cell Behavior in Health, Disease and Regeneration.

Authors:  Luai Huleihel; Michelle E Scarritt; Stephen F Badylak
Journal:  Curr Pathobiol Rep       Date:  2017-02-01

Review 7.  Cerebral Amyloid Angiopathy, Alzheimer's Disease and MicroRNA: miRNA as Diagnostic Biomarkers and Potential Therapeutic Targets.

Authors:  J Weldon Furr; Diego Morales-Scheihing; Bharti Manwani; Juneyoung Lee; Louise D McCullough
Journal:  Neuromolecular Med       Date:  2019-10-04       Impact factor: 3.843

Review 8.  Epigenetic mechanisms of neurodegenerative diseases and acute brain injury.

Authors:  Mario J Bertogliat; Kahlilia C Morris-Blanco; Raghu Vemuganti
Journal:  Neurochem Int       Date:  2019-12-12       Impact factor: 3.921

9.  A Customized Quantitative PCR MicroRNA Panel Provides a Technically Robust Context for Studying Neurodegenerative Disease Biomarkers and Indicates a High Correlation Between Cerebrospinal Fluid and Choroid Plexus MicroRNA Expression.

Authors:  Wang-Xia Wang; David W Fardo; Gregory A Jicha; Peter T Nelson
Journal:  Mol Neurobiol       Date:  2016-11-29       Impact factor: 5.590

10.  Near-infrared spectroscopy (NIRS) and vagus somatosensory evoked potentials (VSEP) in the early diagnosis of Alzheimer's disease: rationale, design, methods, and first baseline data of the Vogel study.

Authors:  Thomas Polak; Martin J Herrmann; Laura D Müller; Julia B M Zeller; Andrea Katzorke; Matthias Fischer; Fabian Spielmann; Erik Weinmann; Leif Hommers; Martin Lauer; Andreas J Fallgatter; Jürgen Deckert
Journal:  J Neural Transm (Vienna)       Date:  2017-09-01       Impact factor: 3.575
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