Literature DB >> 23821693

Successful treatment of refractory autoimmune hepatitis with rituximab.

Daniel D'Agostino1, Alejandro Costaguta, Fernando Álvarez.   

Abstract

Autoimmune hepatitis is a severe liver disease in which ~10% of patients do not respond to standard treatment. We describe a new rescue therapy using anti-CD20 monoclonal antibodies (rituximab). Complete remission was obtained and maintained by using low doses of immunosuppressive drugs with repeated anti-CD20 infusions.

Entities:  

Keywords:  autoimmune hepatitis; children; rituximab; treatment

Mesh:

Substances:

Year:  2013        PMID: 23821693     DOI: 10.1542/peds.2011-1900

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  15 in total

Review 1.  The Contribution of B Cells in Autoimmune Liver Diseases.

Authors:  Sarah A Taylor; David N Assis; Cara L Mack
Journal:  Semin Liver Dis       Date:  2019-06-21       Impact factor: 6.115

Review 2.  Juvenile autoimmune hepatitis: Spectrum of the disease.

Authors:  Giuseppe Maggiore; Silvia Nastasio; Marco Sciveres
Journal:  World J Hepatol       Date:  2014-07-27

Review 3.  Immunopathogenesis of Autoimmune Hepatitis.

Authors:  David N Assis
Journal:  Clin Liver Dis (Hoboken)       Date:  2020-04-04

Review 4.  Autoimmune hepatitis.

Authors:  Farhad Sahebjam; John M Vierling
Journal:  Front Med       Date:  2015-03-06       Impact factor: 4.592

5.  Refractory Autoimmune Hepatitis: Beyond Standard Therapy.

Authors:  Jonah N Rubin; Helen S Te
Journal:  Dig Dis Sci       Date:  2016-01-02       Impact factor: 3.199

Review 6.  Natural history and management of refractory autoimmune hepatitis.

Authors:  Bridget Whitehead; Alyssa Kriegermeier
Journal:  Clin Liver Dis (Hoboken)       Date:  2022-07-22

Review 7.  Immune Inhibitory Properties and Therapeutic Prospects of Transforming Growth Factor-Beta and Interleukin 10 in Autoimmune Hepatitis.

Authors:  Albert J Czaja
Journal:  Dig Dis Sci       Date:  2021-04-09       Impact factor: 3.199

Review 8.  Novel Immunotherapies for Autoimmune Hepatitis.

Authors:  Shamir Cassim; Marc Bilodeau; Catherine Vincent; Pascal Lapierre
Journal:  Front Pediatr       Date:  2017-01-26       Impact factor: 3.418

Review 9.  Novel Diagnostic and Therapeutic Strategies in Juvenile Autoimmune Hepatitis.

Authors:  Marco Sciveres; Silvia Nastasio; Giuseppe Maggiore
Journal:  Front Pediatr       Date:  2019-09-20       Impact factor: 3.418

Review 10.  Autoimmune hepatitis: Standard treatment and systematic review of alternative treatments.

Authors:  Benedetta Terziroli Beretta-Piccoli; Giorgina Mieli-Vergani; Diego Vergani
Journal:  World J Gastroenterol       Date:  2017-09-07       Impact factor: 5.742

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