Literature DB >> 23821271

High-throughput screening using dengue virus reporter genomes.

Wolfgang Fischl1, Ralf Bartenschlager.   

Abstract

Large-scale antiviral drug discovery and systematic identification of host factors promoting or restricting virus replication require robust, scalable, and cost-effective assay systems that allow for high throughput and automation. Here we describe the construction and application of full-length infectious dengue virus reporter genomes for such screening applications.

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Year:  2013        PMID: 23821271     DOI: 10.1007/978-1-62703-484-5_17

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  33 in total

1.  Genome-Wide Mutagenesis of Dengue Virus Reveals Plasticity of the NS1 Protein and Enables Generation of Infectious Tagged Reporter Viruses.

Authors:  Nicholas S Eyre; Stephen M Johnson; Auda A Eltahla; Maria Aloi; Amanda L Aloia; Christopher A McDevitt; Rowena A Bull; Michael R Beard
Journal:  J Virol       Date:  2017-11-14       Impact factor: 5.103

2.  Apolipoprotein E likely contributes to a maturation step of infectious hepatitis C virus particles and interacts with viral envelope glycoproteins.

Authors:  Ji-Young Lee; Eliana G Acosta; Ina Karen Stoeck; Gang Long; Marie-Sophie Hiet; Birthe Mueller; Oliver T Fackler; Stephanie Kallis; Ralf Bartenschlager
Journal:  J Virol       Date:  2014-08-13       Impact factor: 5.103

3.  A Combined Genetic-Proteomic Approach Identifies Residues within Dengue Virus NS4B Critical for Interaction with NS3 and Viral Replication.

Authors:  Laurent Chatel-Chaix; Wolfgang Fischl; Pietro Scaturro; Mirko Cortese; Stephanie Kallis; Marie Bartenschlager; Bernd Fischer; Ralf Bartenschlager
Journal:  J Virol       Date:  2015-04-29       Impact factor: 5.103

4.  Determinants in Nonstructural Protein 4A of Dengue Virus Required for RNA Replication and Replication Organelle Biogenesis.

Authors:  Mirko Cortese; Klaas Mulder; Laurent Chatel-Chaix; Pietro Scaturro; Berati Cerikan; Anna Plaszczyca; Uta Haselmann; Marie Bartenschlager; Christopher J Neufeldt; Ralf Bartenschlager
Journal:  J Virol       Date:  2021-08-11       Impact factor: 5.103

5.  Characterization of the mode of action of a potent dengue virus capsid inhibitor.

Authors:  Pietro Scaturro; Iuni Margaret Laura Trist; David Paul; Anil Kumar; Eliana G Acosta; Chelsea M Byrd; Robert Jordan; Andrea Brancale; Ralf Bartenschlager
Journal:  J Virol       Date:  2014-07-23       Impact factor: 5.103

6.  Identification of Estrogen Receptor Modulators as Inhibitors of Flavivirus Infection.

Authors:  Emily N Kirby; Daniel R Anfiteatro; Gustavo Bracho; Amanda L Aloia; Michael R Beard; Nicholas S Eyre; Alice G Russo; Peter A White
Journal:  Antimicrob Agents Chemother       Date:  2020-07-22       Impact factor: 5.191

7.  Hepatitis C Virus Replication Depends on Endosomal Cholesterol Homeostasis.

Authors:  Ina Karen Stoeck; Ji-Young Lee; Keisuke Tabata; Inés Romero-Brey; David Paul; Philipp Schult; Volker Lohmann; Lars Kaderali; Ralf Bartenschlager
Journal:  J Virol       Date:  2017-12-14       Impact factor: 5.103

8.  Cytotoxicity and Antiviral Properties of Alkaloids Isolated from Pancratium maritimum.

Authors:  Marco Masi; Roberta Di Lecce; Natacha Mérindol; Marie-Pierre Girard; Lionel Berthoux; Isabel Desgagné-Penix; Viola Calabrò; Antonio Evidente
Journal:  Toxins (Basel)       Date:  2022-04-07       Impact factor: 5.075

9.  Live Cell Analysis and Mathematical Modeling Identify Determinants of Attenuation of Dengue Virus 2'-O-Methylation Mutant.

Authors:  Bianca Schmid; Melanie Rinas; Alessia Ruggieri; Eliana Gisela Acosta; Marie Bartenschlager; Antje Reuter; Wolfgang Fischl; Nathalie Harder; Jan-Philip Bergeest; Michael Flossdorf; Karl Rohr; Thomas Höfer; Ralf Bartenschlager
Journal:  PLoS Pathog       Date:  2015-12-31       Impact factor: 6.823

10.  Dengue Virus Non-structural Protein 1 Modulates Infectious Particle Production via Interaction with the Structural Proteins.

Authors:  Pietro Scaturro; Mirko Cortese; Laurent Chatel-Chaix; Wolfgang Fischl; Ralf Bartenschlager
Journal:  PLoS Pathog       Date:  2015-11-12       Impact factor: 6.823

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