Value of C-reactive protein in detecting complications after open-heart surgery in children.

Measurements of serum C-reactive protein (CRP) and body temperature daily for 14 days after primary open-heart surgery were retrospectively reviewed in 206 children with mean age 4.6 years. CRP rose postoperatively, reaching maximum (128 +/- 57 mg/l) on day 2. Postoperative complications occurred in 78 children (38%), 14 of whom died. CRP concentrations were significantly higher in patients with complications than in those with uneventful recovery. Rising age was associated with greater elevation of CRP levels. Body temperature was higher in children with complications. The age of the child thus modified the CRP response to surgery and to postoperative complications. Serial measurements of CRP may be useful in detecting postoperative complications in children who have undergone open-heart surgery.