OBJECTIVE: To investigate the time-specific effect of maternal exposure to prenatal stressful life events (SLEs) on gestational weight gain (GWG) and to determine whether pre-pregnancy body mass index (BMI) modifies the effect. METHODS: Between March and November 2008, data were collected from 1800 pregnant women who received prenatal check-ups in Hefei, China, after 32 completed weeks of gestation. Participants completed a structured interview on demographic characteristics and a checklist of SLEs during different stages of pregnancy. GWG during pregnancy was determined by self-reported pre-pregnancy weight and measured weight at delivery. RESULTS: There was a significant dose-response relationship between prenatal SLEs in the first, but not the second or third, trimester and GWG. For each 1-unit increase in SLEs during the first trimester, there was a reduction in GWG of approximately 0.497 kg (95% confidence interval, 0.176-0.817 kg). After stratification by pre-pregnancy BMI, a significant negative association between SLEs in the first trimester and GWG was observed among women with pre-pregnancy normal (β=-0.796; 95% CI, -1.291 to -0.301) and low (β=-1.066; 95% CI, -2.180 to -0.048) weight. CONCLUSION: The effect of prenatal SLEs on GWG depends on the timing of maternal exposure to stress and varies according to pre-pregnancy BMI.
OBJECTIVE: To investigate the time-specific effect of maternal exposure to prenatal stressful life events (SLEs) on gestational weight gain (GWG) and to determine whether pre-pregnancy body mass index (BMI) modifies the effect. METHODS: Between March and November 2008, data were collected from 1800 pregnant women who received prenatal check-ups in Hefei, China, after 32 completed weeks of gestation. Participants completed a structured interview on demographic characteristics and a checklist of SLEs during different stages of pregnancy. GWG during pregnancy was determined by self-reported pre-pregnancy weight and measured weight at delivery. RESULTS: There was a significant dose-response relationship between prenatal SLEs in the first, but not the second or third, trimester and GWG. For each 1-unit increase in SLEs during the first trimester, there was a reduction in GWG of approximately 0.497 kg (95% confidence interval, 0.176-0.817 kg). After stratification by pre-pregnancy BMI, a significant negative association between SLEs in the first trimester and GWG was observed among women with pre-pregnancy normal (β=-0.796; 95% CI, -1.291 to -0.301) and low (β=-1.066; 95% CI, -2.180 to -0.048) weight. CONCLUSION: The effect of prenatal SLEs on GWG depends on the timing of maternal exposure to stress and varies according to pre-pregnancy BMI.
Authors: Irene Headen; Mahasin Mujahid; Julianna Deardorff; David H Rehkopf; Barbara Abrams Journal: Health Place Date: 2018-06-05 Impact factor: 4.078
Authors: Jessica Galin; Barbara Abrams; Stephanie A Leonard; Ellicott C Matthay; Dana E Goin; Jennifer Ahern Journal: Paediatr Perinat Epidemiol Date: 2016-12-06 Impact factor: 3.980
Authors: Mufiza Zia Kapadia; Anca Gaston; Sherry Van Blyderveen; Louis Schmidt; Joseph Beyene; Helen McDonald; Sarah D McDonald Journal: BMC Pregnancy Childbirth Date: 2015-05-02 Impact factor: 3.007