OBJECTIVE: We investigated the performance of magnetic resonance imaging (MRI) compared to conventional radiographs for detection of chronic structural changes in the sacroiliac joints (SIJ) in patients with axial spondyloarthritis (SpA). METHODS: We included 112 patients with definite axial SpA (68 with ankylosing spondylitis and 44 with nonradiographic axial SpA), for whom radiographs and MRI scans of the SIJ performed at the same time were available. Radiographs and MRI of the SIJ were scored for subchondral sclerosis (score 0-2), erosions (score 0-3), and joint space changes (score 0-5) in each SIJ. Readers provided an overall impression of the extent of damage according to the scoring system of the modified New York criteria. RESULTS: In total, 224 SIJ from 112 patients were available for analysis. There was rather low agreement between MRI and radiographs concerning definite erosions of SIJ (κ = 0.11), moderate agreement for definite subchondral sclerosis (κ = 0.46) and definite joint space abnormalities (κ = 0.41), and almost perfect agreement for joint ankylosis (κ = 0.85). MRI demonstrated a good overall performance in detection of definite "chronic" sacroiliitis, with a sensitivity of 84% and a specificity of 61%. For sacroiliitis fulfilling the modified New York criteria, MRI had a sensitivity of 81% and a specificity of 64% using radiographs as the reference method. CONCLUSION: MRI demonstrated good overall performance for detection of chronic structural changes in the SIJ as compared to radiographs.
OBJECTIVE: We investigated the performance of magnetic resonance imaging (MRI) compared to conventional radiographs for detection of chronic structural changes in the sacroiliac joints (SIJ) in patients with axial spondyloarthritis (SpA). METHODS: We included 112 patients with definite axial SpA (68 with ankylosing spondylitis and 44 with nonradiographic axial SpA), for whom radiographs and MRI scans of the SIJ performed at the same time were available. Radiographs and MRI of the SIJ were scored for subchondral sclerosis (score 0-2), erosions (score 0-3), and joint space changes (score 0-5) in each SIJ. Readers provided an overall impression of the extent of damage according to the scoring system of the modified New York criteria. RESULTS: In total, 224 SIJ from 112 patients were available for analysis. There was rather low agreement between MRI and radiographs concerning definite erosions of SIJ (κ = 0.11), moderate agreement for definite subchondral sclerosis (κ = 0.46) and definite joint space abnormalities (κ = 0.41), and almost perfect agreement for joint ankylosis (κ = 0.85). MRI demonstrated a good overall performance in detection of definite "chronic" sacroiliitis, with a sensitivity of 84% and a specificity of 61%. For sacroiliitis fulfilling the modified New York criteria, MRI had a sensitivity of 81% and a specificity of 64% using radiographs as the reference method. CONCLUSION: MRI demonstrated good overall performance for detection of chronic structural changes in the SIJ as compared to radiographs.
Authors: Charlotte Jacquemin; Roxana Rubio Vargas; Rosaline van den Berg; Fabrice Thévenin; Gregory Lenczner; Monique Reijnierse; Salah Ferkal; Philippe Le Corvoisier; Alain Rahmouni; Damien Loeuille; Antoine Feydy; Maxime Dougados; Désirée van der Heijde; Pascal Claudepierre Journal: RMD Open Date: 2016-11-11
Authors: Juan C Rueda; Sofia Arias-Correal; Andres Y Vasquez; Enrique Calvo; Paola Peña; Marlon Porras; Jose-Ignacio Angarita; Eugenia-Lucia Saldarriaga; Ana M Santos; John Londono Journal: Int J Rheumatol Date: 2017-02-13
Authors: Désirée van der Heijde; Joachim Sieper; Walter P Maksymowych; Robert G Lambert; Su Chen; Maja Hojnik; Jaclyn K Anderson; Aileen L Pangan Journal: Arthritis Res Ther Date: 2018-03-27 Impact factor: 5.156