Literature DB >> 238184

Cyclization of uridine monophosphate by diethyl pyrocarbonate.

F Solymosy, L Ehrenberg, I Fedorcsák.   

Abstract

Reaction between diethyl pyrocarbonate and uridine 2'-phosphate or uridine 3'-phosphate leads to the formation in high yields of uridine 2':3'-cyclic phosphate. This reaction product was identified in experiments involving (a) ultraviolet spectrophotometry, (b) paper chromatography, (c) high voltage paper electrophoresis at both pH 3.5 and 7.4, (d) acid hydrolysis, and (e) digestion with pancreatic ribonuclease.

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Year:  1975        PMID: 238184      PMCID: PMC343484          DOI: 10.1093/nar/2.6.985

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  4 in total

1.  Nucleotide exchange reactions catalysed by ribonuclease and spleen phosphodiesterase. II. Synthesis of polynucleotides.

Authors:  L A HEPPEL; P R WHITFELD; R MARKHAM
Journal:  Biochem J       Date:  1955-05       Impact factor: 3.857

2.  The structure of ribonucleic acid. I. Cyclic nucleotides produced by ribonuclease and by alkaline hydrolysis.

Authors:  R MARKHAM; J D SMITH
Journal:  Biochem J       Date:  1952-12       Impact factor: 3.857

3.  Reaction of diethyl pyrocarbonate with nucleic acid components. Adenosine-containing nucleotides and dinucleoside phosphates.

Authors:  R E Henderson; L H Kirkegaard; N J Leonard
Journal:  Biochim Biophys Acta       Date:  1973-02-04

4.  Reaction of diethyl pyrocarbonate with nucleic acid components. Bases and nucleosides derived from guanine, cytosine, and uracil.

Authors:  A Vincze; R E Henderson; J J McDonald; N J Leonard
Journal:  J Am Chem Soc       Date:  1973-04-18       Impact factor: 15.419

  4 in total

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