| Literature DB >> 23815851 |
Hilda Samimi1, Majid Zaki Dizaji, Mohsen Ghadami, Abolhasan Shahzadeh Fazeli, Patricia Khashayar, Masoud Soleimani, Bagher Larijani, Vahid Haghpanah.
Abstract
miRNAs are non coding ribonucleic acids which are protected with respect to evolution, and have a length of 18-25 nucleotides. microRNAs control the gene expression after transcription, through mRNA destruction or translation processing, and therefore participate in arrangement of the physiologic and pathologic cellular processes; They also may act as oncogene or tumor suppressors. Altered expression of a number of microRNAs is reported in process of progression and metastasis of thyroid cancers. Therefore, identification of these microRNAs may shed a light to oncogenesis pathway of thyroid cancers and their metastasis. In addition, microRNAs might apply as potential biological markers in diagnosis and treatment of thyroid cancers. The changes made in miRNAs profile of thyroid cancers are reviewed in this paper.Entities:
Year: 2013 PMID: 23815851 PMCID: PMC7976609 DOI: 10.1186/2251-6581-12-31
Source DB: PubMed Journal: J Diabetes Metab Disord ISSN: 2251-6581