Literature DB >> 23814786

Solid phase click ligation for the synthesis of very long oligonucleotides.

Jieqiong Qiu1, Afaf H El-Sagheer, Tom Brown.   

Abstract

Oligonucleotides have been ligated efficiently on solid-phase using CuAAC and SPAAC chemistry to produce up to 186-mer triazole linked DNA products. Multiple sequential ligation reactions can be carried out by using a masked azide approach. This work suggests a novel modular approach to the synthesis of large complex oligonucleotide analogues.

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Year:  2013        PMID： 23814786     DOI： 10.1039/c3cc42451k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

1.  Simple and efficient synthesis of 5'-aryl-5'-deoxyguanosine analogs by azide-alkyne click reaction and their antileishmanial activities.

Authors:  Pierre Daligaux; Sébastien Pomel; Karine Leblanc; Philippe M Loiseau; Christian Cavé
Journal:  Mol Divers       Date:  2016-01-11       Impact factor: 2.943

2.  ClickSeq: Fragmentation-Free Next-Generation Sequencing via Click Ligation of Adaptors to Stochastically Terminated 3'-Azido cDNAs.

Authors:  Andrew Routh; Steven R Head; Phillip Ordoukhanian; John E Johnson
Journal:  J Mol Biol       Date:  2015-06-24       Impact factor: 5.469

Review 3.  Stable RNA nanoparticles as potential new generation drugs for cancer therapy.

Authors:  Yi Shu; Fengmei Pi; Ashwani Sharma; Mehdi Rajabi; Farzin Haque; Dan Shu; Markos Leggas; B Mark Evers; Peixuan Guo
Journal:  Adv Drug Deliv Rev       Date:  2013-11-22       Impact factor: 15.470

4.  Parallel ClickSeq and Nanopore sequencing elucidates the rapid evolution of defective-interfering RNAs in Flock House virus.

Authors:  Elizabeth Jaworski; Andrew Routh
Journal:  PLoS Pathog       Date:  2017-05-05       Impact factor: 6.823

5.  Simultaneous multiple single nucleotide polymorphism detection based on click chemistry combined with DNA-encoded probes.

Authors:  Qian-Yu Zhou; Fang Yuan; Xiao-Hui Zhang; Ying-Lin Zhou; Xin-Xiang Zhang
Journal:  Chem Sci       Date:  2018-02-22       Impact factor: 9.825

6.  Combining triazole ligation and enzymatic glycosylation on solid phase simplifies the synthesis of very long glycoprotein analogues.

Authors:  Mathieu Galibert; Véronique Piller; Friedrich Piller; Vincent Aucagne; Agnès F Delmas
Journal:  Chem Sci       Date:  2015-04-14       Impact factor: 9.825

7.  Copper-free click chemistry for attachment of biomolecules in magnetic tweezers.

Authors:  Jorine M Eeftens; Jaco van der Torre; Daniel R Burnham; Cees Dekker
Journal:  BMC Biophys       Date:  2015-09-25       Impact factor: 4.778

8.  Synthesis of triazole-linked morpholino oligonucleotides via Cu(I) catalysed cycloaddition.

Authors:  Matthew J Palframan; Rima D Alharthy; Paulina K Powalowska; Christopher J Hayes
Journal:  Org Biomol Chem       Date:  2016-02-24       Impact factor: 3.876

9.  Conjugation and Evaluation of Triazole-Linked Single Guide RNA for CRISPR-Cas9 Gene Editing.

Authors:  Kaizhang He; Eldon T Chou; Shawn Begay; Emily M Anderson; Anja van Brabant Smith
Journal:  Chembiochem       Date:  2016-08-19       Impact factor: 3.164
  9 in total

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