Literature DB >> 23814192

Post-traumatic delayed onset pectoralis myospasm secondary to α-γ dysfunction.

Dennis L Barnett1, Klinton McGhee, Paul Bungee.   

Abstract

A restrained motor vehicle accident victim suffered from delayed onset left pectoralis myospasms refractory to multiple treatments: behavioural, conservative, physical therapy, opiate, muscle relaxer and incomplete response to invasive pain management spinal blocks. After conduction of a literature review, several authors had noted the mechanism of α-γ loop dysfunction resulting in myospams, and also case studies which described painful postsurgical myospasms that were treated with neurectomy and/or botulinum toxin A with successful results. The patient in this case underwent an initial lidocaine injection to observe response to treatment, followed by two treatments with botulinum toxin A treatment with subsequent resolution of symptoms. Successful therapy and previous research supports that botulinum toxin A can be an effective treatment for myospasms secondary to trauma-induced α-γ dysfunction, as suggested by the cellular pathophysiology.

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Year:  2013        PMID: 23814192      PMCID: PMC3702832          DOI: 10.1136/bcr-2012-008519

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  7 in total

1.  Permanent reorganization of Ia afferent synapses on motoneurons after peripheral nerve injuries.

Authors:  Francisco J Alvarez; Katie L Bullinger; Haley E Titus; Paul Nardelli; Timothy C Cope
Journal:  Ann N Y Acad Sci       Date:  2010-06       Impact factor: 5.691

2.  Painful pectoralis major myospasm as a result of sternal wound reconstruction: complete resolution with bilateral pectoral neurectomies.

Authors:  B A Mast
Journal:  Plast Reconstr Surg       Date:  1999-09       Impact factor: 4.730

3.  Spike-evoked suppression and burst patterning in dorsal root ganglion neurons of the rat.

Authors:  R Amir; M Devor
Journal:  J Physiol       Date:  1997-05-15       Impact factor: 5.182

4.  Gamma loop dysfunction in the quadriceps femoris of patients who underwent anterior cruciate ligament reconstruction remains bilaterally.

Authors:  Y Konishi; Y Aihara; M Sakai; G Ogawa; T Fukubayashi
Journal:  Scand J Med Sci Sports       Date:  2006-06-28       Impact factor: 4.221

Review 5.  Quadriceps arthrogenic muscle inhibition: neural mechanisms and treatment perspectives.

Authors:  David Andrew Rice; Peter John McNair
Journal:  Semin Arthritis Rheum       Date:  2009-12-02       Impact factor: 5.532

6.  Botulinum toxin infiltration for pain control after mastectomy and expander reconstruction.

Authors:  Rakhshanda Layeeque; Julio Hochberg; Eric Siegel; Kelly Kunkel; Julie Kepple; Ronda S Henry-Tillman; Melinda Dunlap; John Seibert; V Suzanne Klimberg
Journal:  Ann Surg       Date:  2004-10       Impact factor: 12.969

7.  Assessment of the potential role of muscle spindle mechanoreceptor afferents in chronic muscle pain in the rat masseter muscle.

Authors:  James P Lund; Somayeh Sadeghi; Tuija Athanassiadis; Nadia Caram Salas; François Auclair; Benoît Thivierge; Isabel Arsenault; Pierre Rompré; Karl-Gunnar Westberg; Arlette Kolta
Journal:  PLoS One       Date:  2010-06-15       Impact factor: 3.240

  7 in total

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