Literature DB >> 23813997

Advanced testicular cancer in a society of racial and socio-economic health disparity.

Michael Kaufman1.   

Abstract

This is the case of an African-American man who presented with a 6 month history of impressive unilateral testicular swelling and abdominal pain. After a thorough workup he was found to have metastatic testicular seminoma causing multiple complex sequelae. This case highlights the essential diagnostic and therapeutic features of a common malignancy seen primarily in young men. His advanced disease presentation, complex management of multiple comorbidities combined with his African-American race and lower socio-economic status (SES) highlight an unusual paradigm shift in testicular cancer epidemiology from the more typical high SES Caucasian to the lower SES, less educated male patient. Beyond the unexpected clinical presentation, this case then presents multiple avenues of discussion regarding the unfortunate effects of racial disparities on disease presentation and progression that are plaguing our healthcare system today.

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Year:  2013        PMID: 23813997      PMCID: PMC3702991          DOI: 10.1136/bcr-2013-009277

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  26 in total

1.  Clinical pattern and therapeutic results achieved in 1490 patients with germ-cell tumours of the testis: the experience of the Spanish Germ-Cell Cancer Group (GG).

Authors:  J R Germà-Lluch; X Garcia del Muro; P Maroto; L Paz-Ares; J A Arranz; J Gumà; E Alba; J Sastre; J Aparicio; A Fernández; A Barnadas; J Terrassa; A Sáenz; D Almenar; M López-Brea; M A Climent; M A Sánchez; R Lasso de la Vega; G Berenguer; X Pérez
Journal:  Eur Urol       Date:  2002-12       Impact factor: 20.096

2.  The role of alpha-fetoprotein and human chorionic gonadotropin in seminoma.

Authors:  N Javadpour; K R McIntire; T A Waldmann; S M Bergman
Journal:  J Urol       Date:  1978-12       Impact factor: 7.450

3.  Racial disparities and socioeconomic status in men diagnosed with testicular germ cell tumors: a survival analysis.

Authors:  Maxine Sun; Firas Abdollah; Daniel Liberman; Al'a Abdo; Rodolphe Thuret; Zhe Tian; Shahrokh F Shariat; Francesco Montorsi; Paul Perrotte; Pierre I Karakiewicz
Journal:  Cancer       Date:  2011-03-08       Impact factor: 6.860

4.  Hyperglycosylated human chorionic gonadotropin in serum of testicular cancer patients.

Authors:  Anna Lempiäinen; Kristina Hotakainen; Carl Blomqvist; Henrik Alfthan; Ulf-Håkan Stenman
Journal:  Clin Chem       Date:  2012-04-23       Impact factor: 8.327

5.  Retroperitoneal histologic findings of patients with elevated serum alpha-fetoprotein and pure seminoma at orchiectomy.

Authors:  Shilajit D Kundu; Brett S Carver; Joel Sheinfeld
Journal:  Urology       Date:  2011-07-22       Impact factor: 2.649

6.  Socio-economic inequalities in testicular cancer survival within two clinical studies.

Authors:  Ula Nur; Bernard Rachet; Mahesh K B Parmar; Mathew R Sydes; Nicola Cooper; Sally Stenning; Graham Read; Tim Oliver; Malcolm Mason; Michel P Coleman
Journal:  Cancer Epidemiol       Date:  2011-09-03       Impact factor: 2.984

7.  Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer.

Authors:  Agnes Y Y Lee; Mark N Levine; Ross I Baker; Chris Bowden; Ajay K Kakkar; Martin Prins; Frederick R Rickles; Jim A Julian; Susan Haley; Michael J Kovacs; Michael Gent
Journal:  N Engl J Med       Date:  2003-07-10       Impact factor: 91.245

8.  Socio-economic differences in incidence rates of cancers of the male genital organs in Finland, 1971-95.

Authors:  Eero Pukkala; Elisabete Weiderpass
Journal:  Int J Cancer       Date:  2002-12-20       Impact factor: 7.396

9.  Some social and medical characteristics of Army men with testicular cancer.

Authors:  A S Morrison
Journal:  Am J Epidemiol       Date:  1976-11       Impact factor: 4.897

10.  Differences in testis cancer survival by race and ethnicity: a population-based study, 1973-1999 (United States).

Authors:  Mary Lou Biggs; Stephen M Schwartz
Journal:  Cancer Causes Control       Date:  2004-06       Impact factor: 2.506

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  1 in total

1.  Testicular Cancer at the University of Port Harcourt Teaching Hospital: A 10-year Retrospective Review.

Authors:  V Abhulimen; E J Raphael
Journal:  J West Afr Coll Surg       Date:  2022-01-05
  1 in total

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