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Literature DB >> 23813938

Response: the role of RUNX1 isoforms in hematopoietic commitment of human pluripotent stem cells.

Dan Ran, Kentson Lam, Wei-Jong Shia, Miao-Chia Lo, Jun-Bao Fan, David A Knorr, Patrick I Ferrell, Zhaohui Ye, Ming Yan, Linzhao Cheng, Dan S Kaufman, Dong-Er Zhang.

Abstract

Entities: Gene Species

Mesh：

Substances：

Year: 2013 PMID： 23813938 PMCID： PMC3695367 DOI： 10.1182/blood-2013-04-494914

Source DB: PubMed Journal: Blood ISSN： 0006-4971 Impact factor: 22.113

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References

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11 in total

1. The role of RUNX1 isoforms in hematopoietic commitment of human pluripotent stem cells.

Authors: Pedro J Real; Oscar Navarro-Montero; Verónica Ramos-Mejía; Verónica Ayllón; Clara Bueno; Pablo Menéndez
Journal: Blood Date: 2013-06-27 Impact factor: 22.113

2. Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1.

Authors: M S Petrovick; S W Hiebert; A D Friedman; C J Hetherington; D G Tenen; D E Zhang
Journal: Mol Cell Biol Date: 1998-07 Impact factor: 4.272

3. Expansion of functionally defined mouse hematopoietic stem and progenitor cells by a short isoform of RUNX1/AML1.

Authors: Shinobu Tsuzuki; Masao Seto
Journal: Blood Date: 2011-11-30 Impact factor: 22.113

4. Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells.

Authors: Grant A Challen; Margaret A Goodell
Journal: Exp Hematol Date: 2010-03-03 Impact factor: 3.084

5. Runx1 deletion or dominant inhibition reduces Cebpa transcription via conserved promoter and distal enhancer sites to favor monopoiesis over granulopoiesis.

Authors: Hong Guo; Ou Ma; Nancy A Speck; Alan D Friedman
Journal: Blood Date: 2012-03-26 Impact factor: 22.113

10. RUNX1 and its fusion oncoprotein derivative, RUNX1-ETO, induce senescence-like growth arrest independently of replicative stress.

Authors: K Wolyniec; S Wotton; A Kilbey; A Jenkins; A Terry; G Peters; C Stocking; E Cameron; J C Neil
Journal: Oncogene Date: 2009-05-18 Impact factor: 9.867

Response: the role of RUNX1 isoforms in hematopoietic commitment of human pluripotent stem cells.

1. The role of RUNX1 isoforms in hematopoietic commitment of human pluripotent stem cells.

2. Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1.

3. Expansion of functionally defined mouse hematopoietic stem and progenitor cells by a short isoform of RUNX1/AML1.

4. Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells.

5. Runx1 deletion or dominant inhibition reduces Cebpa transcription via conserved promoter and distal enhancer sites to favor monopoiesis over granulopoiesis.

6. RUNX1 transformation of primary embryonic fibroblasts is revealed in the absence of p53.

7. Overexpression of an isoform of AML1 in acute leukemia and its potential role in leukemogenesis.

Review 8. RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis.

9. Isoform-specific potentiation of stem and progenitor cell engraftment by AML1/RUNX1.

10. RUNX1 and its fusion oncoprotein derivative, RUNX1-ETO, induce senescence-like growth arrest independently of replicative stress.