Literature DB >> 23813892

Scalable manufacture of built-to-order nanomedicine: spray-assisted layer-by-layer functionalization of PRINT nanoparticles.

Stephen W Morton1, Kevin P Herlihy, Kevin E Shopsowitz, Zhou J Deng, Kevin S Chu, Charles J Bowerman, Joseph M Desimone, Paula T Hammond.   

Abstract

Scalable methods, PRINT particle fabrication, and spray-assisted Layer-by-Layer deposition are combined to generate uniform and functional nanotechnologies with precise control over composition, size, shape, and surface functionality. A modular and tunable approach towards design of built-to-order nanoparticle systems, spray coating on PRINT particles is demonstrated to achieve technologies capable of targeted interactions with cancer cells for applications in drug delivery.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  core/shell nanoparticles; nanoimprinting; nanomedicine; thin films

Mesh：

Substances：

Year:  2013        PMID： 23813892      PMCID： PMC4040353          DOI： 10.1002/adma.201302025

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  30 in total

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Review 3.  Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles.

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Review 4.  Self-assembled targeted nanoparticles: evolution of technologies and bench to bedside translation.

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5.  A hyaluronic acid-taxol antitumor bioconjugate targeted to cancer cells.

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6.  Liposome-encapsulated doxorubicin targeted to CD44: a strategy to kill CD44-overexpressing tumor cells.

Authors:  R E Eliaz; F C Szoka
Journal:  Cancer Res       Date:  2001-03-15       Impact factor: 12.701

7.  Controlling in vivo stability and biodistribution in electrostatically assembled nanoparticles for systemic delivery.

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Review 8.  Nanocarriers as an emerging platform for cancer therapy.

Authors:  Dan Peer; Jeffrey M Karp; Seungpyo Hong; Omid C Farokhzad; Rimona Margalit; Robert Langer
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Review 9.  Nanoparticle therapeutics: an emerging treatment modality for cancer.

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Authors:  Michael J Lee; Albert S Ye; Alexandra K Gardino; Anne Margriet Heijink; Peter K Sorger; Gavin MacBeath; Michael B Yaffe
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  20 in total

1.  An automated multidimensional thin film stretching device for the generation of anisotropic polymeric micro- and nanoparticles.

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Journal:  J Biomed Mater Res A       Date:  2015-02-24       Impact factor: 4.396

2.  Osteotropic therapy via targeted layer-by-layer nanoparticles.

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Review 3.  Advances in engineering hydrogels.

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4.  Shape Control in Engineering of Polymeric Nanoparticles for Therapeutic Delivery.

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Review 5.  Emerging nanotechnologies for cancer immunotherapy.

Authors:  Sourabh Shukla; Nicole F Steinmetz
Journal:  Exp Biol Med (Maywood)       Date:  2016-05-04

6.  Highly scalable, closed-loop synthesis of drug-loaded, layer-by-layer nanoparticles.

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Review 7.  An overview of clinical and commercial impact of drug delivery systems.

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8.  Layer-by-layer nanoparticles for systemic codelivery of an anticancer drug and siRNA for potential triple-negative breast cancer treatment.

Authors:  Zhou J Deng; Stephen W Morton; Elana Ben-Akiva; Erik C Dreaden; Kevin E Shopsowitz; Paula T Hammond
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9.  Polymeric nanoparticle system to target activated microglia/macrophages in spinal cord injury.

Authors:  Simonetta Papa; Raffaele Ferrari; Massimiliano De Paola; Filippo Rossi; Alessandro Mariani; Ilaria Caron; Eliana Sammali; Marco Peviani; Valentina Dell'Oro; Claudio Colombo; Massimo Morbidelli; Gianluigi Forloni; Giuseppe Perale; Davide Moscatelli; Pietro Veglianese
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Review 10.  Control of polymeric nanoparticle size to improve therapeutic delivery.

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