Literature DB >> 23813366

Preparation of primary microglia cultures from postnatal mouse and rat brains.

Tomas Deierborg1.   

Abstract

Microglia are the inflammatory cells of the brain and are activated in neuropathological conditions. To study the biology of microglia, these cells can be isolated from the brain and analyzed in terms of pro- and anti-inflammatory cytokine production, involvement of intracellular signaling pathways upon inflammatory stimuli, phagocytosis, and several more biological aspects to understand their role in the brain. In this book chapter, I will discuss microglial cells and describe how these cells can be cultured from a postnatal mouse and rat brain.

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Year:  2013        PMID： 23813366     DOI： 10.1007/978-1-62703-520-0_4

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  10 in total

1.  Neuroprotective effects of G-CSF administration in microglia-mediated reactive T cell activation in vitro.

Authors:  Wei Peng
Journal:  Immunol Res       Date:  2017-08       Impact factor: 2.829

2.  Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility.

Authors:  Martin Valdearcos; John D Douglass; Megan M Robblee; Mauricio D Dorfman; Daniel R Stifler; Mariko L Bennett; Irene Gerritse; Rachael Fasnacht; Ben A Barres; Joshua P Thaler; Suneil K Koliwad
Journal:  Cell Metab       Date:  2017-07-05       Impact factor: 27.287

3.  Microglia dictate the impact of saturated fat consumption on hypothalamic inflammation and neuronal function.

Authors:  Martin Valdearcos; Megan M Robblee; Daniel I Benjamin; Daniel K Nomura; Allison W Xu; Suneil K Koliwad
Journal:  Cell Rep       Date:  2014-12-11       Impact factor: 9.423

4.  Puerarin protects against β-amyloid-induced microglia apoptosis via a PI3K-dependent signaling pathway.

Authors:  Cui Wang; Nanchang Xie; Huiru Zhang; Yulin Li; Yunlong Wang
Journal:  Neurochem Res       Date:  2014-08-31       Impact factor: 3.996

5.  The role of Galectin-3 in α-synuclein-induced microglial activation.

Authors:  Antonio Boza-Serrano; Juan F Reyes; Nolwen L Rey; Hakon Leffler; Luc Bousset; Ulf Nilsson; Patrik Brundin; Jose Luis Venero; Miguel Angel Burguillos; Tomas Deierborg
Journal:  Acta Neuropathol Commun       Date:  2014-11-12       Impact factor: 7.801

6.  Brain pericytes acquire a microglial phenotype after stroke.

Authors:  Ilknur Özen; Tomas Deierborg; Kenichi Miharada; Thomas Padel; Elisabet Englund; Guillem Genové; Gesine Paul
Journal:  Acta Neuropathol       Date:  2014-05-22       Impact factor: 17.088

7.  TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss.

Authors:  Rosa C Paolicelli; Ali Jawaid; Christopher M Henstridge; Andrea Valeri; Mario Merlini; John L Robinson; Edward B Lee; Jamie Rose; Stanley Appel; Virginia M-Y Lee; John Q Trojanowski; Tara Spires-Jones; Paul E Schulz; Lawrence Rajendran
Journal:  Neuron       Date:  2017-06-29       Impact factor: 17.173

8.  Microglia P2Y13 Receptors Prevent Astrocyte Proliferation Mediated by P2Y1 Receptors.

Authors:  Clara Quintas; Nuno Vale; Jorge Gonçalves; Glória Queiroz
Journal:  Front Pharmacol       Date:  2018-05-03       Impact factor: 5.810

9.  Deficiency of Tristetraprolin Triggers Hyperthermia through Enhancing Hypothalamic Inflammation.

Authors:  Da Yeon Jeong; Nuri Song; Hye Rim Yang; Thai Hien Tu; Byong Seo Park; Hara Kang; Jeong Woo Park; Byung Ju Lee; Sunggu Yang; Jae Geun Kim
Journal:  Int J Mol Sci       Date:  2021-03-24       Impact factor: 5.923

10.  1-Oleyl-lysophosphatidic acid (LPA) promotes polarization of BV-2 and primary murine microglia towards an M1-like phenotype.

Authors:  Ioanna Plastira; Eva Bernhart; Madeleine Goeritzer; Helga Reicher; Vishwanath Bhat Kumble; Nora Kogelnik; Andrea Wintersperger; Astrid Hammer; Stefanie Schlager; Katharina Jandl; Akos Heinemann; Dagmar Kratky; Ernst Malle; Wolfgang Sattler
Journal:  J Neuroinflammation       Date:  2016-08-26       Impact factor: 9.587
  10 in total

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