Tanja Hildenbrand1. 1. Ear, Nose and Throat Department, University Hospital Freiburg, Killianstr. 5, D-79106 Freiburg, Germany. tanja.hildenbrand@uniklinik-freiburg.de
Abstract
BACKGROUND: To ensure more effective hemostasis in surgical procedures, a novel sponge of pharmaceutical-grade chemically cross-linked gelatine, characterized by a high pore density, reduced ligaments and a high nanoscale roughness of the surface has been developed. PATIENTS AND METHODS: A questionnaire-based survey was carried out at seven ENT centers in Germany to collect clinical data. A total of 62 patients undergoing nasal and sinus surgery were treated with the new product to test its efficacy as a hemostat, its absorptive capacity, its handling in general, and its subsequent biodegradation. RESULTS: In summary, performance regarding the above parameters was very good. No adverse events were observed. The major advantages of this sponge in comparison with other available products were fast hemostasis and that there was no need for removal of the dressing because of its biodegradation.
BACKGROUND: To ensure more effective hemostasis in surgical procedures, a novel sponge of pharmaceutical-grade chemically cross-linked gelatine, characterized by a high pore density, reduced ligaments and a high nanoscale roughness of the surface has been developed. PATIENTS AND METHODS: A questionnaire-based survey was carried out at seven ENT centers in Germany to collect clinical data. A total of 62 patients undergoing nasal and sinus surgery were treated with the new product to test its efficacy as a hemostat, its absorptive capacity, its handling in general, and its subsequent biodegradation. RESULTS: In summary, performance regarding the above parameters was very good. No adverse events were observed. The major advantages of this sponge in comparison with other available products were fast hemostasis and that there was no need for removal of the dressing because of its biodegradation.
Authors: N Oker; V Dupuch; P Herman; N Leclerc; P Vironneau; H Dang; J Majer; R Pastourel; Y Pavier; J-P Blancal; N Saroul; T Mom; R Kania; E Vicaut; L Gilain; B Verillaud Journal: Eur Arch Otorhinolaryngol Date: 2016-08-17 Impact factor: 2.503
Authors: Akhilesh K Gaharwar; Reginald K Avery; Alexander Assmann; Arghya Paul; Gareth H McKinley; Ali Khademhosseini; Bradley D Olsen Journal: ACS Nano Date: 2014-10-08 Impact factor: 15.881