Diane M Mueller1, John J Oro'. 1. Neurosurgery Center of Colorado, Aurora, CO, USA. Diane.Mueller@hcahealthcare.com
Abstract
OBJECTIVE: The Chiari Symptom Profile (CSP) was developed to provide a quantitative assessment of self-reported Chiari (CMI)-related symptoms and their impact on the individual's quality of life. METHODS: The instrument was developed in three phases. Phase I consisted of instrument development using exploratory item analysis from the literature and direct patient evaluations. The item pool was then analyzed and tested on a convenience sample of eight CMI patients. Interitem correlation matrix suggested redundancy of 13 questions. These items were discarded, resulting in a final questionnaire consisting of 57 items, measuring four realms: physical, functional, psychological, and social. Phases II and III tested the reliability and validity of the instrument using a large sample of patients diagnosed with Chiari/syringomyelia. RESULTS: Statistical analysis confirmed that the CSP has excellent validity and reliability with a Cronbach's alpha of .958 (p = .0001) and factor loadings ranging from .784 to .321. CONCLUSION: The CSP is a self-reported, Chiari-/syringomyelia-specific instrument intended to provide a quantitative analysis of symptoms and their impact on the individual's quality of life. The CSP has shown statistically significant content validity, internal consistency, and test-retest reliability. The CSP will enhance the provider's understanding of Chiari-/syringomyelia-related symptoms, quantify the impact of self-reported symptoms on quality of life, help to determine if interventions are of benefit, and allow comparison of symptomatic improvement/outcome following different surgical techniques.
OBJECTIVE: The Chiari Symptom Profile (CSP) was developed to provide a quantitative assessment of self-reported Chiari (CMI)-related symptoms and their impact on the individual's quality of life. METHODS: The instrument was developed in three phases. Phase I consisted of instrument development using exploratory item analysis from the literature and direct patient evaluations. The item pool was then analyzed and tested on a convenience sample of eight CMI patients. Interitem correlation matrix suggested redundancy of 13 questions. These items were discarded, resulting in a final questionnaire consisting of 57 items, measuring four realms: physical, functional, psychological, and social. Phases II and III tested the reliability and validity of the instrument using a large sample of patients diagnosed with Chiari/syringomyelia. RESULTS: Statistical analysis confirmed that the CSP has excellent validity and reliability with a Cronbach's alpha of .958 (p = .0001) and factor loadings ranging from .784 to .321. CONCLUSION: The CSP is a self-reported, Chiari-/syringomyelia-specific instrument intended to provide a quantitative analysis of symptoms and their impact on the individual's quality of life. The CSP has shown statistically significant content validity, internal consistency, and test-retest reliability. The CSP will enhance the provider's understanding of Chiari-/syringomyelia-related symptoms, quantify the impact of self-reported symptoms on quality of life, help to determine if interventions are of benefit, and allow comparison of symptomatic improvement/outcome following different surgical techniques.
Authors: Jacob K Greenberg; Chester K Yarbrough; Alireza Radmanesh; Jakub Godzik; Megan Yu; Donna B Jeffe; Matthew D Smyth; Tae Sung Park; Jay F Piccirillo; David D Limbrick Journal: Neurosurgery Date: 2015-03 Impact factor: 4.654