Hong-Tao Zhang1, Bao-Ping Qiao, Bao-Ping Liu, Xian-Guo Zhao. 1. Blood Purification Center (H-TZ, X-GZ) and Department of Urology (B-PQ), The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Institute of Nephrology (H-TZ), Zhengzhou University, Zhengzhou, China; Key Discipline Laboratory of Clinical Medicine (H-TZ, B-PQ), Jiaozuo, China; and Department of Nuclear Medicine (B-PL), The Second Charity Hospital of Henan Province, Jiaozuo, China.
Abstract
BACKGROUND: Acute thallium poisoning rarely occurs but is a serious and even fatal medical condition. Currently, patients with acute thallium poisoning are usually treated with Prussian blue and blood purification therapy. However, there are few studies about these treatments for acute thallium poisoning. METHODS: Nine patients with acute thallium poisoning from 1 family were treated successfully with Prussian blue and different types of blood purification therapies and analyzed. RESULTS: Prussian blue combined with sequential hemodialysis, hemoperfusion and/or continuous veno-venous hemofiltration were effective for the treatment of patients with acute thallium poisoning, even after delayed diagnosis. CONCLUSIONS: Blood purification therapies help in the clearance of thallium in those with acute thallium poisoning. Prussian blue treatment may do the benefit during this process.
BACKGROUND: Acute thalliumpoisoning rarely occurs but is a serious and even fatal medical condition. Currently, patients with acute thalliumpoisoning are usually treated with Prussian blue and blood purification therapy. However, there are few studies about these treatments for acute thalliumpoisoning. METHODS: Nine patients with acute thalliumpoisoning from 1 family were treated successfully with Prussian blue and different types of blood purification therapies and analyzed. RESULTS:Prussian blue combined with sequential hemodialysis, hemoperfusion and/or continuous veno-venous hemofiltration were effective for the treatment of patients with acute thalliumpoisoning, even after delayed diagnosis. CONCLUSIONS: Blood purification therapies help in the clearance of thallium in those with acute thalliumpoisoning. Prussian blue treatment may do the benefit during this process.
Authors: Thilini D Kondasinghe; Hasina Y Saraha; Shane T Jackowski; Jennifer L Stockdill Journal: Tetrahedron Lett Date: 2018-11-22 Impact factor: 2.415