INTRODUCTION: Toxoplasma gondii is a protozoon parasite that has a worldwide dissemination. It can cause serious clinical problems such as congenital toxoplasmosis, retinochoroiditis, and encephalitis. Currently, T. gondii genotypes are being associated with these clinical presentations which may help clinicians design their treatment strategy. CASE REPORTS: Two T. gondii strains named Ankara and Ege-1 were isolated from newborns with congenital toxoplasmosis in Central and Western Anatolia, respectively. Ankara and Ege-1 strains were isolated from the cerebrospinal fluid of newborns. According to microsatellite analysis, Ankara and Ege-1 strains were sorted as Africa 1 genotype. CONCLUSION: T. gondii strains isolated in Turkey were first time genotyped in this study. Africa 1 genotype has previously been isolated in immunosuppressed patients originating from sub-Saharan Africa. The reason of detecting a strain mainly detected in Africa can be associated with Turkey's specific geographical location. Turkey is like a bridge between Asia, Europe and Africa. Historically, Anatolia was on the Silk Road and other trading routes that ended in Europe. Thus, detecting Africa 1 strain in Anatolia can be anticipated. Consequently, strains detected mainly in Europe and Asia may also be detected in Anatolia and vice versa. Therefore, further studies are required to isolate more strains from Turkey.
INTRODUCTION: Toxoplasma gondii is a protozoon parasite that has a worldwide dissemination. It can cause serious clinical problems such as congenital toxoplasmosis, retinochoroiditis, and encephalitis. Currently, T. gondii genotypes are being associated with these clinical presentations which may help clinicians design their treatment strategy. CASE REPORTS: Two T. gondii strains named Ankara and Ege-1 were isolated from newborns with congenital toxoplasmosis in Central and Western Anatolia, respectively. Ankara and Ege-1 strains were isolated from the cerebrospinal fluid of newborns. According to microsatellite analysis, Ankara and Ege-1 strains were sorted as Africa 1 genotype. CONCLUSION:T. gondii strains isolated in Turkey were first time genotyped in this study. Africa 1 genotype has previously been isolated in immunosuppressed patients originating from sub-Saharan Africa. The reason of detecting a strain mainly detected in Africa can be associated with Turkey's specific geographical location. Turkey is like a bridge between Asia, Europe and Africa. Historically, Anatolia was on the Silk Road and other trading routes that ended in Europe. Thus, detecting Africa 1 strain in Anatolia can be anticipated. Consequently, strains detected mainly in Europe and Asia may also be detected in Anatolia and vice versa. Therefore, further studies are required to isolate more strains from Turkey.
Authors: Jiin Felgner; Silvia Juarez; Chris Hung; L I Liang; Aarti Jain; Mert Döşkaya; Philip L Felgner; Ayşe Caner; Yüksel Gürüz; D Huw Davies Journal: Parasitology Date: 2015-01-14 Impact factor: 3.234
Authors: Waléria Borges-Silva; Mariana M Rezende-Gondim; Gideão S Galvão; Daniele S Rocha; George R Albuquerque; Luís P Gondim Journal: J Vet Diagn Invest Date: 2021-03-10 Impact factor: 1.279
Authors: Hüseyin Can; Mert Döşkaya; Daniel Ajzenberg; H Gökhan Özdemir; Ayşe Caner; Sultan Gülce İz; Aysu Değirmenci Döşkaya; Esra Atalay; Çağdaş Çetinkaya; Saygun Ürgen; Sabire Karaçalı; Cemal Ün; Marie-Laure Dardé; Yüksel Gürüz Journal: PLoS One Date: 2014-08-15 Impact factor: 3.240
Authors: Aleksandra Uzelac; Ivana Klun; Vladimir Ćirković; Neda Bauman; Branko Bobić; Tijana Štajner; Jelena Srbljanović; Olivera Lijeskić; Olgica Djurković-Djaković Journal: Microorganisms Date: 2021-12-07