Literature DB >> 23811102

Dietary exposure of the Belgian adult population to non-dioxin-like PCBs.

Oya Cimenci1, Stefanie Vandevijvere, Séverine Goscinny, Marie-Anne Van Den Bergh, Vincent Hanot, Christine Vinkx, Fabien Bolle, Joris Van Loco.   

Abstract

Non-dioxin-like polychlorinated biphenyls (ndl-PCBs), and some of their metabolites, might initiate neurological, neuroendocrinological, immunological and carcinogenic effects. Dietary exposure of the Belgian adult population to ndl-PCBs was investigated in this study. Foods from five food groups, collected in Belgium in 2008, were analyzed by GC-MS/MS for the six indicator PCBs (PCB 28, 52, 101, 138, 153 and 180). Results were expressed as the sum of the six congeners. A dietary exposure assessment was performed, combining ndl-PCBs levels found in food with data from the national food consumption survey of 2004. Fish and fish products were the dominating food group in terms of contamination level, with the highest levels measured in the composite sample «other fishes» (18.58 ng/g FW). The dietary exposure of the Belgian population (n=3083) to ndl-PCBs ranged from 5.33 ng/kg b.w./day on average to 16.10 ng/kg b.w./day at the 99th percentile, using the lower bound concentration. The mean dietary exposure mainly originates from Fish and fish products (54.3%), followed by dairy products (28.5%). As neither EFSA nor JECFA have set a Tolerable Daily Intake for ndl PCBs, uncertainty remains about how to interpret the exposure data in terms of public health.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Belgian population; Dietary exposure; Food consumption; Non-dioxin-like PCBs

Mesh:

Substances:

Year:  2013        PMID: 23811102     DOI: 10.1016/j.fct.2013.06.020

Source DB:  PubMed          Journal:  Food Chem Toxicol        ISSN: 0278-6915            Impact factor:   6.023


  5 in total

1.  Polychlorinated biphenyl and polybrominated diphenyl ether profiles in serum from cattle, sheep, and goats across California.

Authors:  S Sethi; X Chen; P H Kass; B Puschner
Journal:  Chemosphere       Date:  2017-04-14       Impact factor: 7.086

2.  Developmental exposure to polychlorinated biphenyls (PCBs) in the maternal diet causes host-microbe defects in weanling offspring mice.

Authors:  Kavi M Rude; Matteo M Pusceddu; Ciara E Keogh; Jessica A Sladek; Gonzalo Rabasa; Elaine N Miller; Sunjay Sethi; Kimberly P Keil; Isaac N Pessah; Pamela J Lein; Mélanie G Gareau
Journal:  Environ Pollut       Date:  2019-07-14       Impact factor: 8.071

3.  3,3'-Dichlorobiphenyl (PCB 11) promotes dendritic arborization in primary rat cortical neurons via a CREB-dependent mechanism.

Authors:  Sunjay Sethi; Kimberly P Keil; Pamela J Lein
Journal:  Arch Toxicol       Date:  2018-09-17       Impact factor: 5.153

4.  The influence of sex, genotype, and dose on serum and hippocampal cytokine levels in juvenile mice developmentally exposed to a human-relevant mixture of polychlorinated biphenyls.

Authors:  Lauren Matelski; Kimberly P Keil Stietz; Sunjay Sethi; Sandra L Taylor; Judy Van de Water; Pamela J Lein
Journal:  Curr Res Toxicol       Date:  2020-09-10

5.  PCBs and PCDD/Fs in Bluefin Tuna: Occurrence and Dietary Intake.

Authors:  Grazia Barone; Arianna Storelli; Rita Garofalo; Rosanna Mallamaci; Nicoletta C Quaglia; Maria Maddalena Storelli
Journal:  Int J Environ Res Public Health       Date:  2018-05-03       Impact factor: 3.390

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.