Literature DB >> 23811021

Temporal variation of Trypanosoma cruzi discrete typing units in asymptomatic Chagas disease patients.

Laura V Sánchez1, Diana C Bautista, Andrés F Corredor, Victor M Herrera, Luz X Martinez, Juan Carlos Villar, Juan David Ramírez.   

Abstract

Chagas disease caused by Trypanosoma cruzi is a public health problem in Latin America. This parasite displays a high genetic diversity evidenced in six Discrete Typing Units (DTUs) namely TcI-TcVI. The aim of this study was to observe the temporal variation of the DTUs in asymptomatic patients at three different times (10 days interval). The results showed that intermittence is the rule in the bloodstream of Chagas disease patients. The patients showed different detectable DTUs with short time intervals, which favors the clonal histiotropic model and the multiclonality structure of this parasite. Published by Elsevier Masson SAS.

Entities:  

Keywords:  Chagas disease; Discrete typing unit; Multiclonality; SL-IR; Temporal distribution

Mesh：

Year:  2013        PMID： 23811021     DOI： 10.1016/j.micinf.2013.06.008

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  5 in total

Review 1.  Chagas Disease in the United States: a Public Health Approach.

Authors:  Caryn Bern; Louisa A Messenger; Jeffrey D Whitman; James H Maguire
Journal:  Clin Microbiol Rev       Date:  2019-11-27       Impact factor: 26.132

Review 2.  Between a bug and a hard place: Trypanosoma cruzi genetic diversity and the clinical outcomes of Chagas disease.

Authors:  Louisa A Messenger; Michael A Miles; Caryn Bern
Journal:  Expert Rev Anti Infect Ther       Date:  2015-08       Impact factor: 5.091

3.  Genetic polymorphism of Trypanosoma cruzi bloodstream populations in adult chronic indeterminate Chagas disease patients from the E1224 clinical trial.

Authors:  Juan Carlos Ramírez; Gonzalo Raúl Acevedo; Carolina Torres; Rudy Parrado; Anabelle De La Barra; Sandro Villarroel; Lineth García; Joaquim Gascon; Lourdes Ortiz; Faustino Torrico; Isabela Ribeiro; Alejandro Gabriel Schijman
Journal:  J Antimicrob Chemother       Date:  2022-02-23       Impact factor: 5.790

Review 4.  Over Six Thousand Trypanosoma cruzi Strains Classified into Discrete Typing Units (DTUs): Attempt at an Inventory.

Authors:  Simone Frédérique Brenière; Etienne Waleckx; Christian Barnabé
Journal:  PLoS Negl Trop Dis       Date:  2016-08-29

5.  Genomes of Leishmania parasites directly sequenced from patients with visceral leishmaniasis in the Indian subcontinent.

Authors:  Malgorzata A Domagalska; Hideo Imamura; Mandy Sanders; Frederik Van den Broeck; Narayan Raj Bhattarai; Manu Vanaerschot; Ilse Maes; Erika D'Haenens; Keshav Rai; Suman Rijal; Matthew Berriman; James A Cotton; Jean-Claude Dujardin
Journal:  PLoS Negl Trop Dis       Date:  2019-12-12
  5 in total

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