OBJECTIVE: We retrospectively investigate the prevalence of gynecomastia as false-positive 2-[18F]fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) imaging in patients with hepatocellular carcinoma (HCC). METHODS: Among the 127 male HCC patients who underwent 18F-FDG PET/CT scan, the 18FDG uptakes at the bilateral breasts in 9 patients with gynecomastia were recorded as standard uptake value (SUVmax) and the visual interpretation in both early and delayed images. RESULTS: The mean early SUVmax was 1.58/1.57 (right/left breast) in nine gynecomastia patients. The three patients with early visual score of 3 had higher early SUVmaxs. CONCLUSION: Gynecomastia is a possible cause of false-positive uptake on 18F-FDG PET/CT images.
OBJECTIVE: We retrospectively investigate the prevalence of gynecomastia as false-positive 2-[18F]fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) imaging in patients with hepatocellular carcinoma (HCC). METHODS: Among the 127 male HCCpatients who underwent 18F-FDG PET/CT scan, the 18FDG uptakes at the bilateral breasts in 9 patients with gynecomastia were recorded as standard uptake value (SUVmax) and the visual interpretation in both early and delayed images. RESULTS: The mean early SUVmax was 1.58/1.57 (right/left breast) in nine gynecomastiapatients. The three patients with early visual score of 3 had higher early SUVmaxs. CONCLUSION:Gynecomastia is a possible cause of false-positive uptake on 18F-FDG PET/CT images.