OBJECTIVE: To assist other eye movement investigators in the design and analysis of their studies. METHODS: We examined basic saccadic eye movements and smooth pursuit in the horizontal and vertical directions with video-oculography in a group of 145 healthy subjects between 19 and 82 years of age. RESULTS: Gender and education level did not influence eye movement metrics. With age, the latency of leftward and vertical pro- and antisaccades increased (p<0.001), velocity of upward prosaccades decreased (p<0.001), gain of rightward and upward prosaccades diminished (p<0.001), and the error rate of antisaccades increased (p<0.001). Prosaccades and antisaccades were influenced by the direction of the target, resulting in a right/left and up/down asymmetry. The skewness of the saccade velocity profile was stable throughout the lifespan, and within the range of saccades analyzed in the present study, correlated with amplitude and duration only for antisaccades (p<0.001). CONCLUSIONS: Some eye movement metrics must be separated by the direction of movement, others according to subject age, while others may be pooled. SIGNIFICANCE: This study provides important information for new oculomotor laboratories concerning the constitution of subject groups and the analysis of eye movement metrics.
OBJECTIVE: To assist other eye movement investigators in the design and analysis of their studies. METHODS: We examined basic saccadic eye movements and smooth pursuit in the horizontal and vertical directions with video-oculography in a group of 145 healthy subjects between 19 and 82 years of age. RESULTS: Gender and education level did not influence eye movement metrics. With age, the latency of leftward and vertical pro- and antisaccades increased (p<0.001), velocity of upward prosaccades decreased (p<0.001), gain of rightward and upward prosaccades diminished (p<0.001), and the error rate of antisaccades increased (p<0.001). Prosaccades and antisaccades were influenced by the direction of the target, resulting in a right/left and up/down asymmetry. The skewness of the saccade velocity profile was stable throughout the lifespan, and within the range of saccades analyzed in the present study, correlated with amplitude and duration only for antisaccades (p<0.001). CONCLUSIONS: Some eye movement metrics must be separated by the direction of movement, others according to subject age, while others may be pooled. SIGNIFICANCE: This study provides important information for new oculomotor laboratories concerning the constitution of subject groups and the analysis of eye movement metrics.
Authors: Rachel Yep; Matthew L Smorenburg; Heidi C Riek; Olivia G Calancie; Ryan H Kirkpatrick; Julia E Perkins; Jeff Huang; Brian C Coe; Donald C Brien; Douglas P Munoz Journal: Front Aging Neurosci Date: 2022-05-18 Impact factor: 5.702
Authors: Cecilia Bonnet; Jan Rusz; Marika Megrelishvili; Tomáš Sieger; Olga Matoušková; Michael Okujava; Hana Brožová; Tomáš Nikolai; Jaromír Hanuška; Mariam Kapianidze; Nina Mikeladze; Nazi Botchorishvili; Irine Khatiashvili; Marina Janelidze; Tereza Serranová; Ondřej Fiala; Jan Roth; Jonas Bergquist; Robert Jech; Sophie Rivaud-Péchoux; Bertrand Gaymard; Evžen Růžička Journal: PLoS One Date: 2014-08-12 Impact factor: 3.240
Authors: Diliana Rebelo; Francisco Oliveira; Antero Abrunhosa; Cristina Januário; João Lemos; Miguel Castelo-Branco Journal: Proc Natl Acad Sci U S A Date: 2021-01-19 Impact factor: 12.779