| Literature DB >> 23806110 |
Guoxu Ma1, Jingquan Yuan, Haifeng Wu, Li Cao, Xiaopo Zhang, Lijia Xu, Hua Wei, Lizhen Wu, Qingxia Zheng, Liyong Li, Lijing Zhang, Junshan Yang, Xudong Xu.
Abstract
Eight new cassane-type diterpenes, caesalpins A-H (1-8), were isolated from the ethyl acetate extract of Caesalpinia minax. Compound 1 displayed significant antiproliferative activity against HepG-2 (IC50 4.7 μM) and MCF-7 (IC50 2.1 μM) cells, and compounds 2 and 4 exhibited selective cytotoxic activities against MCF-7 (IC50 7.9 μM) and AGS (IC50 6.5 μM) cells.Entities:
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Year: 2013 PMID： 23806110 DOI： 10.1021/np300918q
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050