| Literature DB >> 23804380 |
Julia Dina1, Stephanie Raymond, Anne Maillard, Helene Le Guillou-Guillemette, Audrey Rodalec, Agnes Beby-Defaux, Genevieve Giraudeau, Sophie Vallet, Thomas Mourez, Christopher Payan, Astrid Vabret, Annick Ruffault, Virginie Ferre, Jacques Izopet, Jean-Christophe Plantier.
Abstract
We compared the coreceptor tropism-predicting performance of a specific genotypic algorithm for HIV-1 subtype D and that of the geno2pheno algorithm with different cutoffs. The D-specific algorithm and geno2pheno with a false-positivity rate cutoff of 2.5% had the same concordance with the phenotypic determination. The geno2pheno algorithm with a false-positivity rate cutoff of 2.5%, more sensitive but slightly less specific, seems to be an appropriate alternative.Entities:
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Year: 2013 PMID: 23804380 PMCID: PMC3754628 DOI: 10.1128/JCM.00798-13
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948