Literature DB >> 23802071

Recruitment of myeloid cells to the tumor microenvironment supports liver metastasis.

Su Yin Lim1, Alex N Gordon-Weeks, Lei Zhao, Thomas T Tapmeier, Jae Hong Im, Yunhong Cao, John Beech, Danny Allen, Sean Smart, Ruth J Muschel.   

Abstract

Tumor-infiltrating immune cells play important roles in metastasis. We have recently revealed the recruitment of a specific myeloid cell subset (CD11b/Gr1mid) to hepatic metastases. Such a recruitment relies on CCL2/CCR2 signaling and acts to sustain metastatic growth. A similar cell subset was identified in patients bearing hepatic metastases of colorectal cancer, highlighting the potential therapeutic relevance of our findings.

Entities:  

Keywords:  CCL2; colon cancer; liver metastasis; myeloid cell recruitment

Year:  2013        PMID： 23802071      PMCID： PMC3661156          DOI： 10.4161/onci.23187

Source DB:  PubMed          Journal:  Oncoimmunology        ISSN： 2162-4011            Impact factor:   8.110


  8 in total

Review 1.  Cancer-related inflammation: common themes and therapeutic opportunities.

Authors:  Frances R Balkwill; Alberto Mantovani
Journal:  Semin Cancer Biol       Date:  2011-12-24       Impact factor: 15.707

2.  Inactivation of chemokine (C-C motif) receptor 1 (CCR1) suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model.

Authors:  Takanori Kitamura; Teruaki Fujishita; Pius Loetscher; Laszlo Revesz; Hiroki Hashida; Shinae Kizaka-Kondoh; Masahiro Aoki; Makoto M Taketo
Journal:  Proc Natl Acad Sci U S A       Date:  2010-06-29       Impact factor: 11.205

3.  Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes.

Authors:  Marcin Kowanetz; Xiumin Wu; John Lee; Martha Tan; Thijs Hagenbeek; Xueping Qu; Lanlan Yu; Jed Ross; Nina Korsisaari; Tim Cao; Hani Bou-Reslan; Dara Kallop; Robby Weimer; Mary J C Ludlam; Joshua S Kaminker; Zora Modrusan; Nicholas van Bruggen; Franklin V Peale; Richard Carano; Y Gloria Meng; Napoleone Ferrara
Journal:  Proc Natl Acad Sci U S A       Date:  2010-11-16       Impact factor: 11.205

4.  CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis.

Authors:  Bin-Zhi Qian; Jiufeng Li; Hui Zhang; Takanori Kitamura; Jinghang Zhang; Liam R Campion; Elizabeth A Kaiser; Linda A Snyder; Jeffrey W Pollard
Journal:  Nature       Date:  2011-06-08       Impact factor: 49.962

5.  Significance of monocyte chemoattractant protein-1 in angiogenesis and survival in colorectal liver metastases.

Authors:  Hiroyuki Yoshidome; Hirohiko Kohno; Takashi Shida; Fumio Kimura; Hiroaki Shimizu; Masayuki Ohtsuka; Yukio Nakatani; Masaru Miyazaki
Journal:  Int J Oncol       Date:  2009-04       Impact factor: 5.650

6.  Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis.

Authors:  Li Yang; Jianhua Huang; Xiubao Ren; Agnieszka E Gorska; Anna Chytil; Mary Aakre; David P Carbone; Lynn M Matrisian; Ann Richmond; P Charles Lin; Harold L Moses
Journal:  Cancer Cell       Date:  2008-01       Impact factor: 31.743

7.  Tumor cell-microenvironment interaction models coupled with clinical validation reveal CCL2 and SNCG as two predictors of colorectal cancer hepatic metastasis.

Authors:  Hai Hu; Lichao Sun; Chunguang Guo; Qian Liu; Zhuan Zhou; Liang Peng; Jian Pan; Long Yu; Jinning Lou; Zhihua Yang; Ping Zhao; Yuliang Ran
Journal:  Clin Cancer Res       Date:  2009-08-25       Impact factor: 12.531

8.  Recruitment of a myeloid cell subset (CD11b/Gr1 mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis.

Authors:  Lei Zhao; Su Yin Lim; Alex N Gordon-Weeks; Thomas T Tapmeier; Jae Hong Im; Yunhong Cao; John Beech; Danny Allen; Sean Smart; Ruth J Muschel
Journal:  Hepatology       Date:  2013-01-08       Impact factor: 17.425
  8 in total
  7 in total

Review 1.  Molecular Pathways: Deciphering Mechanisms of Resistance to Macrophage-Targeted Therapies.

Authors:  Daniela F Quail; Johanna A Joyce
Journal:  Clin Cancer Res       Date:  2016-11-28       Impact factor: 12.531

2.  Tumour Microenvironment: Overview with an Emphasis on the Colorectal Liver Metastasis Pathway.

Authors:  Alexandros Giakoustidis; Satvinder Mudan; Thorsten Hagemann
Journal:  Cancer Microenviron       Date:  2014-10-03

3.  Evolving polarisation of infiltrating and alveolar macrophages in the lung during metastatic progression of melanoma suggests CCR1 as a therapeutic target.

Authors:  Thomas T Tapmeier; Jake H Howell; Lei Zhao; Bartlomiej W Papiez; Julia A Schnabel; Ruth J Muschel; Annamaria Gal
Journal:  Oncogene       Date:  2022-10-14       Impact factor: 8.756

4.  IL-33 promotes growth and liver metastasis of colorectal cancer in mice by remodeling the tumor microenvironment and inducing angiogenesis.

Authors:  Yu Zhang; Celestia Davis; Sapana Shah; Daniel Hughes; James C Ryan; Diego Altomare; Maria Marjorette O Peña
Journal:  Mol Carcinog       Date:  2016-04-27       Impact factor: 4.784

5.  Granulocytic immune infiltrates are essential for the efficient formation of breast cancer liver metastases.

Authors:  Sébastien Tabariès; Véronique Ouellet; Brian E Hsu; Matthew G Annis; April A N Rose; Liliane Meunier; Euridice Carmona; Christine E Tam; Anne-Marie Mes-Masson; Peter M Siegel
Journal:  Breast Cancer Res       Date:  2015-03-27       Impact factor: 6.466

Review 6.  The role of chemoattractant receptors in shaping the tumor microenvironment.

Authors:  Jiamin Zhou; Yi Xiang; Teizo Yoshimura; Keqiang Chen; Wanghua Gong; Jian Huang; Ye Zhou; Xiaohong Yao; Xiuwu Bian; Ji Ming Wang
Journal:  Biomed Res Int       Date:  2014-07-10       Impact factor: 3.411

Review 7.  Trial Watch: Proteasomal inhibitors for anticancer therapy.

Authors:  Florine Obrist; Gwenola Manic; Guido Kroemer; Ilio Vitale; Lorenzo Galluzzi
Journal:  Mol Cell Oncol       Date:  2014-12-01
  7 in total

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