Literature DB >> 23801847

Colonic mucormycosis presented with ischemic colitis in a liver transplant recipient.

Gi Won Do1, Seok Won Jung, Jae-Bum Jun, Jae Hee Seo, Yang Won Nah.   

Abstract

Mucormycosis is an uncommon opportunistic fungal infection with high mortality in liver transplant recipients. Mucormycosis of the gastrointestinal tract can manifest with features similar to ischemic colitis. Typically signs and symptoms of non-gangrenous ischemic colitis resolve spontaneously within 24-48 h. On the other hand, the clinical course of the mucormycosis is commonly fulminant. We encountered a case of invasive fungal colitis presenting with abdominal pain and hematochezia in a liver transplant recipient. Endoscopic examination showed multiple shallow ulcerations and edema with mucosal friabilities on the sigmoid and distal descending colon, which was consistent with ischemic colitis. However, the histological examination obtained from endoscopic biopsies showed fungal hyphae with surrounding inflammatory cells and mucosal necrosis. The patient was successfully managed with antifungal agent without surgical treatment. Thus, early diagnosis and treatment is essential for improving the prognosis of invasive fungal infection after liver transplantation.

Entities:  

Keywords:  Colon; Ischemia; Liver transplantation; Mucormycosis

Mesh:

Substances:

Year:  2013        PMID: 23801847      PMCID: PMC3683693          DOI: 10.3748/wjg.v19.i22.3508

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  10 in total

Review 1.  Chapter 7: zygomycosis.

Authors:  Cecília Bittencourt Severo; Luciana Silva Guazzelli; Luiz Carlos Severo
Journal:  J Bras Pneumol       Date:  2010 Jan-Feb       Impact factor: 2.624

Review 2.  Zygomycosis in solid organ transplant recipients in a tertiary transplant center and review of the literature.

Authors:  N G Almyroudis; D A Sutton; P Linden; M G Rinaldi; J Fung; S Kusne
Journal:  Am J Transplant       Date:  2006-08-21       Impact factor: 8.086

Review 3.  Novel perspectives on mucormycosis: pathophysiology, presentation, and management.

Authors:  Brad Spellberg; John Edwards; Ashraf Ibrahim
Journal:  Clin Microbiol Rev       Date:  2005-07       Impact factor: 26.132

Review 4.  Ischemic colitis: a clinical review.

Authors:  Bryan T Green; David A Tendler
Journal:  South Med J       Date:  2005-02       Impact factor: 0.954

Review 5.  Gastrointestinal mucormycosis mimicking ischemic colitis in a patient with systemic lupus erythematosus.

Authors:  M Hosseini; J Lee
Journal:  Am J Gastroenterol       Date:  1998-08       Impact factor: 10.864

6.  Hepatic and renal artery rupture due to Aspergillus and Mucor mixed infection after combined liver and kidney transplantation: a case report.

Authors:  H X Zhan; Y Lv; Y Zhang; C Liu; B Wang; Y Y Jiang; X M Liu
Journal:  Transplant Proc       Date:  2008-06       Impact factor: 1.066

7.  Endoscopic findings and clinicopathologic characteristics of ischemic colitis: a report of 85 cases.

Authors:  Xiaoping Zou; Jun Cao; Yulin Yao; Wenjia Liu; Longdian Chen
Journal:  Dig Dis Sci       Date:  2008-12-17       Impact factor: 3.199

8.  Zygomycosis in solid organ transplant recipients: a prospective, matched case-control study to assess risks for disease and outcome.

Authors:  Nina Singh; Jose M Aguado; Hugo Bonatti; Graeme Forrest; Krishan L Gupta; Nasia Safdar; George T John; Kenneth J Pursell; Patricia Muñoz; Robin Patel; Jesus Fortun; Pilar Martin-Davila; Bruno Philippe; François Philit; Alexis Tabah; Nicolas Terzi; Valérie Chatelet; Shimon Kusne; Nina Clark; Emily Blumberg; Marino Blanes Julia; Abhi Humar; Sally Houston; Cornelia Lass-Flörl; Leonard Johnson; Erik R Dubberke; Michelle A Barron; Olivier Lortholary
Journal:  J Infect Dis       Date:  2009-09-15       Impact factor: 5.226

9.  Colonoscopy is a useful diagnostic tool for transplant recipients with lower abdominal symptoms.

Authors:  M Korkmaz; G Gür; U Yilmaz; H Karakayali; S Boyacioğlu; M Haberal
Journal:  Transplant Proc       Date:  2004 Jan-Feb       Impact factor: 1.066

Review 10.  Successful nonoperative management of gastrointestinal mucormycosis: novel therapy for invasive disease.

Authors:  James J Mezhir; Kathleen M Mullane; Joel Zarling; Rohit Satoskar; Rish K Pai; Kevin K Roggin
Journal:  Surg Infect (Larchmt)       Date:  2009-10       Impact factor: 2.150

  10 in total
  2 in total

1.  Gastrointestinal mucormycosis initially manifest as hematochezia from arterio-enteric fistula.

Authors:  Jordan M Cloyd; Janice Brown; Tiffany Sinclair; David Jenks; Jay Desai; Teri Longacre; Venita Chandra; Andy Shelton
Journal:  Dig Dis Sci       Date:  2014-12       Impact factor: 3.199

Review 2.  CT appearance of gastrointestinal tract mucormycosis.

Authors:  Samarjit Singh Ghuman; Pendyala Sindhu; T B S Buxi; Swapnil Sheth; Anurag Yadav; Kishan Singh Rawat; Seema Sud
Journal:  Abdom Radiol (NY)       Date:  2020-11-10
  2 in total

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