Literature DB >> 237998

Isolation, characterization and quantitation of chloral hydrate as a transient metabolite of trichloroethylene in man using electron capture gas chromatography and mass fragmentography.

W J Cole, R G Mitchell, R F Salamonsen.   

Abstract

A method for the quantitative determination of plasma concentrations of chloral hydrate by electron capture gas chromatography is described. Characterization by multiple ion monitoring confirms, for the first time, that chloral hydrate exists as a transient metabolite of trichloroethylene in man.

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Year:  1975        PMID： 237998     DOI： 10.1111/j.2042-7158.1975.tb09431.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN： 0022-3573            Impact factor:   3.765


  5 in total

Review 1.  Industrial toxicants and Parkinson's disease.

Authors:  W Michael Caudle; Thomas S Guillot; Carlos R Lazo; Gary W Miller
Journal:  Neurotoxicology       Date:  2012-01-30       Impact factor: 4.294

2.  Developmental toxicity of trichloroethylene, tetrachloroethylene and four of their metabolites in rat whole embryo culture.

Authors:  A M Saillenfait; I Langonné; J P Sabaté
Journal:  Arch Toxicol       Date:  1995       Impact factor: 5.153

3.  1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) Alters Cell Cycle Progression in Human Neuroblastoma Cell Lines.

Authors:  Rakesh Kumar Sharma; Eduardo Candelario-Jalil; Doris Feineis; Gerhard Bringmann; Bernd L Fiebich; Ravi Shankar Akundi
Journal:  Neurotox Res       Date:  2017-07-18       Impact factor: 3.911

4.  Metabolism of halogenated ethylenes.

Authors:  K C Leibman; E Ortiz
Journal:  Environ Health Perspect       Date:  1977-12       Impact factor: 9.031

Review 5.  Mode of action of liver tumor induction by trichloroethylene and its metabolites, trichloroacetate and dichloroacetate.

Authors:  R J Bull
Journal:  Environ Health Perspect       Date:  2000-05       Impact factor: 9.031
  5 in total

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