Inbreeding effects on reproductive outcome in a Sudanese population.

926 women attending the Obstetrics and Gynaecology Department of the Faculty of Medicine, Khartoum, were investigated to study the inbreeding effects on reproductive profiles and morbidity of the offspring. 49.5% of the women had married their first cousins and 13.8% had married more distant relatives. Altogether, 4,471 pregnancy outcomes were analysed including abortions, still births, neonatal and childhood deaths, physical deformity, mental retardation and other congenital abnormalities. No significant difference in the reproductive loss or net fertility was observed between the inbred and outbred groups. Only the proportions of childhood deaths were found to be significantly higher in the inbred marriages (p less than 0.005). The morbidity was also not affected by the practice of inbreeding.