Literature DB >> 2379484

[Different predisposition to the development of spontaneous and induced liver tumors in mice of different strains and their hybrids].

V I Kaledin, I A Serova, L A Semenova.   

Abstract

No correlation between the sensitivity to induction of liver tumours by ortho-aminoazotoluene and predisposition to spontaneous development of these tumours was found in mice. Under crossing the predisposition to spontaneous tumours was inherited dominantly, while sensitivity to their induction was inherited by the intermediate type. Spontaneous hepatomas were more frequent in males, whereas induced onesin females of the same genotype.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2379484

Source DB:  PubMed          Journal:  Eksp Onkol        ISSN： 0204-3564


  5 in total

1.  The mechanisms of endogenous control of hepatocyte proliferation are different in mice of two inbred strains (BALB/c and AKR).

Authors:  A V Eremeev; O A Timofeeva; V I Kaledin; N A Setkov
Journal:  Dokl Biol Sci       Date:  2002 Mar-Apr

2.  Phenobarbital does not reduce the concentration of thyroid hormone in CC57BR mice in which it does not promote liver tumor development.

Authors:  V I Kaledin; T A Obut
Journal:  Dokl Biol Sci       Date:  2003 Nov-Dec

3.  Ortho-aminoazotoluene activates mouse constitutive androstane receptor (mCAR) and increases expression of mCAR target genes.

Authors:  Mariya A Smetanina; Mariya Y Pakharukova; Svitlana M Kurinna; Bingning Dong; Juan P Hernandez; David D Moore; Tatyana I Merkulova
Journal:  Toxicol Appl Pharmacol       Date:  2011-06-06       Impact factor: 4.219

4.  Orto-aminoazotoluen induces the expression of the p53 gene in inbred strains of mice susceptible and resistant to hepatocarcinogenesis.

Authors:  O A Timofeeva; A V Eremeev; A N Goloshchapov; S I Ilnitskaya; T I Merculova; V I Kaledin; N A Setkov
Journal:  Dokl Biol Sci       Date:  2009 Nov-Dec

5.  O-aminoazotoluene suppresses hepatocyte proliferation in inbred mice susceptible to hepatocarcinogenesis.

Authors:  A V Eremeev; O A Timofeeva; A V Goloshchapov; S I Il'nitskaya; T I Merkulova; V I Kaledin; N A Setkov
Journal:  Dokl Biol Sci       Date:  2009 Sep-Oct
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.