Literature DB >> 23794517

Functional antibody CDR3 fusion proteins with enhanced pharmacological properties.

Yong Zhang1, Danling Wang, Lorenzo de Lichtervelde, Sophie B Sun, Vaughn V Smider, Peter G Schultz, Feng Wang.   

Abstract

Entities:  

Keywords:  antibodies; pharmacology; polypeptide; protein engineering; ultralong CDR

Mesh：

Substances：

Year:  2013        PMID： 23794517      PMCID： PMC3783209          DOI： 10.1002/anie.201303656

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  19 in total

Review 1.  Antibody pharmacokinetics and pharmacodynamics.

Authors:  Evelyn D Lobo; Ryan J Hansen; Joseph P Balthasar
Journal:  J Pharm Sci       Date:  2004-11       Impact factor: 3.534

2.  Use of a single VH family and long CDR3s in the variable region of cattle Ig heavy chains.

Authors:  S J Berens; D E Wylie; O J Lopez
Journal:  Int Immunol       Date:  1997-01       Impact factor: 4.823

3.  Efficient mobilization of haematopoietic progenitors after a single injection of pegylated recombinant human granulocyte colony-stimulating factor in mouse strains with distinct marrow-cell pool sizes.

Authors:  G de Haan; A Ausema; M Wilkens; G Molineux; B Dontje
Journal:  Br J Haematol       Date:  2000-09       Impact factor: 6.998

Review 4.  A single VH family and long CDR3s are the targets for hypermutation in bovine immunoglobulin heavy chains.

Authors:  O Lopez; C Perez; D Wylie
Journal:  Immunol Rev       Date:  1998-04       Impact factor: 12.988

5.  A new bioassay for human granulocyte colony-stimulating factor (hG-CSF) using murine myeloblastic NFS-60 cells as targets and estimation of its levels in sera from normal healthy persons and patients with infectious and hematological disorders.

Authors:  N Shirafuji; S Asano; S Matsuda; K Watari; F Takaku; S Nagata
Journal:  Exp Hematol       Date:  1989-02       Impact factor: 3.084

6.  Reshaping antibody diversity.

Authors:  Feng Wang; Damian C Ekiert; Insha Ahmad; Wenli Yu; Yong Zhang; Omar Bazirgan; Ali Torkamani; Terje Raudsepp; Waithaka Mwangi; Michael F Criscitiello; Ian A Wilson; Peter G Schultz; Vaughn V Smider
Journal:  Cell       Date:  2013-06-06       Impact factor: 41.582

7.  Enhanced circulating half-life and hematopoietic properties of a human granulocyte colony-stimulating factor/immunoglobulin fusion protein.

Authors:  George N Cox; Darin J Smith; Sharon J Carlson; Alison M Bendele; Elizabeth A Chlipala; Daniel H Doherty
Journal:  Exp Hematol       Date:  2004-05       Impact factor: 3.084

8.  Crystal structure of canine and bovine granulocyte-colony stimulating factor (G-CSF).

Authors:  B Lovejoy; D Cascio; D Eisenberg
Journal:  J Mol Biol       Date:  1993-12-05       Impact factor: 5.469

9.  Effect of granulocyte colony stimulating factor on neutropenia induced by cytotoxic chemotherapy.

Authors:  G Morstyn; L Campbell; L M Souza; N K Alton; J Keech; M Green; W Sheridan; D Metcalf; R Fox
Journal:  Lancet       Date:  1988-03-26       Impact factor: 79.321

10.  Bovine IgM antibodies with exceptionally long complementarity-determining region 3 of the heavy chain share unique structural properties conferring restricted VH + Vlambda pairings.

Authors:  Surinder S Saini; William Farrugia; Paul A Ramsland; Azad K Kaushik
Journal:  Int Immunol       Date:  2003-07       Impact factor: 4.823
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  13 in total

Review 1.  Structural and genetic diversity in antibody repertoires from diverse species.

Authors:  Miguel de los Rios; Michael F Criscitiello; Vaughn V Smider
Journal:  Curr Opin Struct Biol       Date:  2015-07-17       Impact factor: 6.809

2.  Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies.

Authors:  David T Rodgers; Magdalena Mazagova; Eric N Hampton; Yu Cao; Nitya S Ramadoss; Ian R Hardy; Andrew Schulman; Juanjuan Du; Feng Wang; Oded Singer; Jennifer Ma; Vanessa Nunez; Jiayin Shen; Ashley K Woods; Timothy M Wright; Peter G Schultz; Chan Hyuk Kim; Travis S Young
Journal:  Proc Natl Acad Sci U S A       Date:  2016-01-12       Impact factor: 11.205

Review 3.  Distinct antibody species: structural differences creating therapeutic opportunities.

Authors:  Serge Muyldermans; Vaughn V Smider
Journal:  Curr Opin Immunol       Date:  2016-02-27       Impact factor: 7.486

Review 4.  Combinatorial antibody libraries: new advances, new immunological insights.

Authors:  Richard A Lerner
Journal:  Nat Rev Immunol       Date:  2016-07-04       Impact factor: 53.106

5.  Rational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant.

Authors:  Rongsheng E Wang; Ying Wang; Yuhan Zhang; Chase Gabrelow; Yong Zhang; Victor Chi; Qiangwei Fu; Xiaozhou Luo; Danling Wang; Sean Joseph; Kristen Johnson; Arnab K Chatterjee; Timothy M Wright; Vân T B Nguyen-Tran; John Teijaro; Argyrios N Theofilopoulos; Peter G Schultz; Feng Wang
Journal:  Proc Natl Acad Sci U S A       Date:  2016-09-23       Impact factor: 11.205

6.  An antibody with a variable-region coiled-coil "knob" domain.

Authors:  Yong Zhang; Devrishi Goswami; Danling Wang; Tsung-Shing Andrew Wang; Shiladitya Sen; Thomas J Magliery; Patrick R Griffin; Feng Wang; Peter G Schultz
Journal:  Angew Chem Int Ed Engl       Date:  2013-11-19       Impact factor: 15.336

7.  Functional human antibody CDR fusions as long-acting therapeutic endocrine agonists.

Authors:  Tao Liu; Yong Zhang; Yan Liu; Ying Wang; Haiqun Jia; Mingchao Kang; Xiaozhou Luo; Dawna Caballero; Jose Gonzalez; Lance Sherwood; Vanessa Nunez; Danling Wang; Ashley Woods; Peter G Schultz; Feng Wang
Journal:  Proc Natl Acad Sci U S A       Date:  2015-01-20       Impact factor: 11.205

8.  Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies.

Authors:  Robyn L Stanfield; Ian A Wilson; Vaughn V Smider
Journal:  Sci Immunol       Date:  2016-07-14

9.  Active-site MMP-selective antibody inhibitors discovered from convex paratope synthetic libraries.

Authors:  Dong Hyun Nam; Carlos Rodriguez; Albert G Remacle; Alex Y Strongin; Xin Ge
Journal:  Proc Natl Acad Sci U S A       Date:  2016-12-13       Impact factor: 11.205

10.  An antibody CDR3-erythropoietin fusion protein.

Authors:  Yong Zhang; Danling Wang; Gus Welzel; Ying Wang; Peter G Schultz; Feng Wang
Journal:  ACS Chem Biol       Date:  2013-08-14       Impact factor: 5.100
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